152333-94-3

Basic information

• Product Name: Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester
• CAS NO: 152333-94-3
• Molecular Formula: C9H9NO6S
• Molecular Weight: 259.24
• Mol File: 152333-94-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester(152333-94-3)
• EPA Substance Registry System: Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester(152333-94-3)

Safety Data

• Hazardous Substances Data: 152333-94-3(Hazardous Substances Data)

Upstream product

• 121-51-7 3-nitrobenzenesulphonyl chloride 
• 57044-25-4 (R)-oxiranemethanol 
• 556-52-5 oxiranyl-methanol 

Downstream Products

• 115314-14-2 (2s)-(+)-glycidyl 3-nitrobenzenesulfonate 
• 115314-14-2 (R)-glycidyl nosylate 
• 5332-66-1 Glycidyl m-nitrophenyl ether 
• 140406-65-1 2-(oxiran-2-ylmethyl)-1,2,3,4-tetrahydroisoquinoline 
• 198226-62-9 (+/-)-2-chloro-6-(oxiran-2-ylmethoxy)benzonitrile 
• 1427034-75-0 2-(5-bromo-2-(oxiran-2-ylmethoxy)phenyl)-1H-indole 
• 2212-04-6 1-(2-chlorophenoxy)-2,3-epoxypropane 
• 335165-60-1 3[4-(3',4'-dichlorophenyl)piperazinyl]-1,2-epoxypropane 
• 51997-51-4 4-(2,3-epoxypropoxy)carbazole 
• 133024-37-0 (+/-)-1-benzyloxy-4-(oxiranylmethoxy)naphthalene 
• 98-47-5 3-Nitrobenzenesulfonic acid 
• 111452-72-3 1-(diphenylmethyl)-4-(2,3-epoxypropyl)piperazine 
• 335165-57-6 benzyl-4-(2,3-epoxypropyl)-piperazine 
• 5255-75-4 C₉H₉NO₄ 

Relevant articles and documents

COMPOUNDS USEFUL IN THE TREATMENT OR PREVENTION OF A PRMT5-MEDIATED DISORDER

The present disclosure relates to compounds suitable for the inhibition of protein arginine methyl-transferase (PRMT), in particular PRMT5. These compounds may be for use as therapeutic agents, in particular, agents for use in the treatment and/or prevent

Synthesis of the calcilytic ligand NPS 2143

(R)-3 (NPS 2143) is a negative allosteric modulator of the human calcium-sensing receptor (CaSR) and as such represents an important pharmacological tool compound for studying the CaSR. Herein, we disclose for the first time a complete experimental description, detailed characterisation and assessment of enantiomeric purity for (R)-3. An efficient, reproducible and scalable synthesis of (R)-3 that requires a minimum of chromatographic purification steps is presented. (R)-3 was obtained in excellent optical purity (er > 99:1) as demonstrated by chiral HPLC and the pharmacological profile for (R)-3 is in full accordance with that reported in the literature.

Bispidine antiarrhythmic compounds

There is provided a compound of formula I, wherein R1, R2, R9, R10, R11, R12, X, A and B have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.