15266-38-3 Usage
General Description
Evocarpine is a chemical compound extracted from the Evodia rutaecarpa plant, also known as Wu Chu Yu in traditional Chinese medicine. It is a quinazolinocarboline alkaloid with potential pharmacological benefits, including anti-inflammatory, anti-cancer, and neuroprotective properties. Evocarpine has been studied for its potential effects on reducing inflammation, inhibiting tumor growth, and protecting against neurodegenerative diseases such as Alzheimer's. It has also been found to modulate the activity of neurotransmitters, such as dopamine and serotonin, and may have potential applications in the treatment of psychiatric disorders. Overall, evocarpine shows promise as a natural compound with diverse pharmacological properties and potential therapeutic uses.
Check Digit Verification of cas no
The CAS Registry Mumber 15266-38-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,6 and 6 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 15266-38:
(7*1)+(6*5)+(5*2)+(4*6)+(3*6)+(2*3)+(1*8)=103
103 % 10 = 3
So 15266-38-3 is a valid CAS Registry Number.
InChI:InChI=1/C23H33NO/c1-3-4-5-6-7-8-9-10-11-12-13-15-20-16-14-17-21-22(25)18-19-24(2)23(20)21/h12-14,16-19H,3-11,15H2,1-2H3/b13-12+
15266-38-3Relevant articles and documents
The Chemistry of 2H-3,1-Benzoxazine-2,4(1H)-dione (Isatoic Anhydride). 17. Synthesis of 2-Alkyl-4-quinolone Alkaloids via a One-step Reaction of N-Methylisatoic Anhydride with Methyl Ketone Enolates
Coppola, Gary M.
, p. 491 - 494 (2007/10/02)
Lithium enolates derived from aliphatic methyl ketones react with N-methylisatoic anhydride (5) at -78 deg C to give 2-alkyl-4-quinolone alkaloids 7 in a single step.The method was used to synthesize both double bond isomers of 1-methyl-2-(8-tridecenyl)-4(1H)-quinolinone (8) thereby showing that the alkaloid evocarpine possesses the Z-olefin stereochemistry 8a.Reduction of 8a provided the alkaloid dihydroevocarpine (16).Compound 16 was also directly prepared from the reaction of 5 with the lithium enolate of 2-pentadecanone.
