1526933-07-2Relevant articles and documents
Synthesis and properties of α-bromomethyl-substituted β-ethoxyvinyl polyfluoroalkyl ketones
Bugera, Maksym Ya.,Tarasenko, Karen V.,Kukhar, Valery P.,R?schenthaler, Gerd-Volker,Gerus, Igor I.
, p. 3157 - 3163 (2013/12/04)
An efficient and practical method for the synthesis of α-bromomethyl- substituted β-alkoxyvinyl polyfluoroalkyl ketones is reported. These highly functionalized α-bromomethyl enones easily react with various nucleophiles and binucleophiles affording a wide variety of new functionalized enones and heterocyclic systems that are perspective starting materials for the synthesis of compounds with potentially high biological and pharmacological activity. Georg Thieme Verlag Stuttgart New York.