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152811-62-6

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152811-62-6 Usage

Description

PIBOSEROD,2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE, N-((1-BUTYL-4-PIPERIDINYL)METHYL)-3,4-DIHYDROis a chemical compound with a complex structure, characterized by its 2H-(1,3)oxazino(3,2-a)indole-10-carboxamide backbone and N-((1-butyl-4-piperidinyl)methyl)-3,4-dihydro substituents. This molecule has potential applications in various fields due to its unique properties and interactions.

Uses

Used in Pharmaceutical Industry:
PIBOSEROD,2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE, N-((1-BUTYL-4-PIPERIDINYL)METHYL)-3,4-DIHYDROis used as a treatment for irritable bowel syndrome (IBS) due to its selective 5HT4 receptor antagonist properties. This application helps alleviate the symptoms associated with IBS by blocking the action of serotonin on the 5HT4 receptors, leading to improved gut motility and reduced abdominal pain.
Used in Hepatitis C Treatment:
In the field of infectious diseases, PIBOSEROD,2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE, N-((1-BUTYL-4-PIPERIDINYL)METHYL)-3,4-DIHYDROhas shown promise as a Hepatitis C virus (HCV) entry inhibitor. As a 5-HT4 receptor antagonist, it can potentially prevent the virus from entering host cells, thereby limiting the spread of the infection and aiding in the treatment of Hepatitis C.

Biochem/physiol Actions

SB-207266 is a potent, selective, orally active and long-acting 5-HT4 antagonist in vivo.

Check Digit Verification of cas no

The CAS Registry Mumber 152811-62-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,8,1 and 1 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 152811-62:
(8*1)+(7*5)+(6*2)+(5*8)+(4*1)+(3*1)+(2*6)+(1*2)=116
116 % 10 = 6
So 152811-62-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H31N3O2/c1-2-3-11-24-13-9-17(10-14-24)16-23-21(26)20-18-7-4-5-8-19(18)25-12-6-15-27-22(20)25/h4-5,7-8,17H,2-3,6,9-16H2,1H3,(H,23,26)

152811-62-6 Well-known Company Product Price

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  • (Code)Product description
  • CAS number
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  • Sigma

  • (SML1349)  SB-207266  ≥98% (HPLC)

  • 152811-62-6

  • SML1349-5MG

  • 1,107.99CNY

  • Detail
  • Sigma

  • (SML1349)  SB-207266  ≥98% (HPLC)

  • 152811-62-6

  • SML1349-25MG

  • 4,469.40CNY

  • Detail

152811-62-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[(1-butylpiperidin-4-yl)methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide

1.2 Other means of identification

Product number -
Other names Piboserod

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:152811-62-6 SDS

152811-62-6Downstream Products

152811-62-6Relevant articles and documents

N--3,4-dihydro-2H-oxazinoindole-10-carboxamide Hydrochloride: The First Potent and Selective 5-HT4 Receptor Antagonist Amide with Oral Activity

Gaster, Laramie M.,Joiner, Graham F.,King, Frank D.,Wyman, Paul A.,Sutton, Jonathan M.,et al.

, p. 4760 - 4763 (1995)

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