153435-81-5 Usage
General Description
4-(3-Bromobenzoyl) Morpholine is a chemical compound with the molecular formula of C11H12BrNO2. It is also known by its IUPAC name - Morpholine, 4-[3-(bromophenyl)-1-oxobutyl]-. This organic compound belongs to the class of morpholines - organic compounds containing a morpholine ring which is a saturated aliphatic six-member ring with one nitrogen atom and one oxygen atom, with the nitrogen atom at the 1-position. 4-(3-Bromobenzoyl) Morpholine is frequently used as a reagent in the synthesis of other chemical compounds, contributing its unique structural properties to more complex molecules. The presence of a bromine atom facilitates various reactions including coupling reactions, making it invaluable in the field of medicinal chemistry, particularly for drug synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 153435-81-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,4,3 and 5 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 153435-81:
(8*1)+(7*5)+(6*3)+(5*4)+(4*3)+(3*5)+(2*8)+(1*1)=125
125 % 10 = 5
So 153435-81-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H12BrNO2/c12-10-3-1-2-9(8-10)11(14)13-4-6-15-7-5-13/h1-3,8H,4-7H2
153435-81-5Relevant articles and documents
Ligand- and Solvent-Tuned Chemoselective Carbonylation of Bromoaryl Triflates
Shen, Chaoren,Wei, Zhihong,Jiao, Haijun,Wu, Xiao-Feng
, p. 13369 - 1337 (2017)
The palladium-catalyzed chemoselective carbonylation of bromoaryl triflates is reported. The selective C?Br bond versus C?OTf (OTf=triflate) bond functionalization can be remarkably tuned by the combination of the ligand [4,5-bis(diphenylphosphino)-9,9-dimethylxanthene (Xantphos) vs. 1,1′-bis(diphenylphosphino)ferrocene (DPPF)] and the solvent (toluene vs. DMSO). The respective ligand and solvent effects are rationalized by DFT calculations. In contrast, the monodentate ligands BuPAd2 and tBu3P prefer the selective C?Br bond activation and are solvent insensitive.
PHENOXY ACETIC ACID DERIVATIVES
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Page/Page column 135, (2010/09/03)
The present invention provides phenoxyacetic acid derivatives of Formula (I) for the treatment of CRTH2 related disorders and disease selected from asthma, atopic dermatitis and inflammatory dermatoses.
