153505-33-0

Basic information

• Product Name: 3-chloro-5-fluorobenzene-1,2-diaMine
• Synonyms: 3-chloro-5-fluorobenzene-1,2-diaMine;1,2-BenzenediaMine, 3-chloro-5-fluoro-
• CAS NO: 153505-33-0
• Molecular Formula: C6H6ClFN2
• Molecular Weight: 160.5766432
• Mol File: 153505-33-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 279.5±35.0 °C(Predicted)
• Appearance: /
• Density: 1.457±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 2.28±0.10(Predicted)
• CAS DataBase Reference: 3-chloro-5-fluorobenzene-1,2-diaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-5-fluorobenzene-1,2-diaMine(153505-33-0)
• EPA Substance Registry System: 3-chloro-5-fluorobenzene-1,2-diaMine(153505-33-0)

Safety Data

• Hazardous Substances Data: 153505-33-0(Hazardous Substances Data)

Usage

General Description

3-chloro-5-fluorobenzene-1,2-diamine, also known as 3,5-Diamino-2-chlorofluorobenzene, is a chemical compound with the molecular formula C6H6ClFN2. It is a derivative of benzene and contains both amine and halogen functional groups. 3-chloro-5-fluorobenzene-1,2-diaMine is commonly used as a building block in the synthesis of various pharmaceuticals, agrochemicals, dyes, and other organic compounds. Its unique structure and reactivity make it a valuable intermediate in organic chemistry, and it is often used in the production of specialty chemicals. 3-chloro-5-fluorobenzene-1,2-diamine is a versatile compound with a wide range of potential applications in the chemical industry.

Upstream product

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Relevant articles and documents

2-aminopyrimidine compounds and application thereof

The invention relates to 2-aminopyrimidine compounds with structures as shown in a formula I which is described in the specification, and pharmaceutically acceptable salts, stereoisomers or prodrug molecules thereof, belonging to the technical field of chemical medicines. The compounds are capable of realizing high-selectivity inhibition of the activity of the FGFR4 protein kinase without inhibition of the activities of other member kinases (i.e., FGFR1, FGFR2 and FGFR3) in the FGFRs family. The compounds can effectively inhibit the growth of tumor cells caused by the abnormity of a FGFR4 signaling pathway, and is applicable to prevention and treatment of transitional proliferative diseases such as tumors in human beings and other mammals caused by the abnormity of the FGFR4 signaling pathway.

Glycine receptor antagonists and the use thereof

Methods of treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma, hypoglycemia and surgery, as well as treating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease and Down's syndrome, treating or preventing the adverse consequences of the hyperactivity of the excitatory amino acids, as well as treating anxiety, chronic pain, convulsions, inducing anesthesia and treating psychosis are disclosed by administering to an animal in need of such treatment a compound having high affinity for the glycine binding site, lacking PCP side effects and which crosses the blood brain barrier of the animal. Also disclosed are novel 1,4-dihydroquinoxaline-2,3-diones, and pharmaceutical compositions thereof. Also disclosed are highly soluble ammonium salts of 1,4-dihydroquinoxaline-2,3-diones.