153888-27-8 Usage
General Description
The chemical (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-ethyl-piperidine is a compound with a piperidine ring structure and a hydroxymethyl group attached to the third carbon atom. It also contains an ethyl group and a fluorophenyl group. (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-ethyl-piperidine is a stereoisomer with a specific arrangement of substituents on the piperidine ring. It may have potential pharmaceutical or medicinal applications due to its structural features, but further research and testing would be needed to determine its specific properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 153888-27-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,8,8 and 8 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 153888-27:
(8*1)+(7*5)+(6*3)+(5*8)+(4*8)+(3*8)+(2*2)+(1*7)=168
168 % 10 = 8
So 153888-27-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H20FNO/c1-2-16-8-7-14(12(9-16)10-17)11-3-5-13(15)6-4-11/h3-6,12,14,17H,2,7-10H2,1H3/t12-,14-/m0/s1
153888-27-8Relevant articles and documents
Structural determinants influencing the potency and selectivity of indazole-paroxetine hybrid G protein-coupled receptor kinase 2 inhibitors
Bouley, Renee,Waldschmidt, Helen V.,Cato, M. Claire,Cannavo, Alessandro,Song, Jianliang,Cheung, Joseph Y.,Yao, Xin-Qiu,Koch, Walter J.,Larsen, Scott D.,Tesmer, John J.G.
supporting information, p. 707 - 717 (2017/11/23)
G protein-coupled receptor kinases (GRKs) phosphorylate activated receptors to promote arrestin binding, decoupling from heterotrimeric G proteins, and internalization. GRK2 and GRK5 are overexpressed in the failing heart and thus have become therapeutic
