1541198-39-3

Basic information

• Product Name: C₁₁H₁₀ClF₃O
• Synonyms: C₁₁H₁₀ClF₃O
• CAS NO: 1541198-39-3
• Molecular Weight: 250.648
• Mol File: 1541198-39-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₁H₁₀ClF₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₁₀ClF₃O(1541198-39-3)
• EPA Substance Registry System: C₁₁H₁₀ClF₃O(1541198-39-3)

Safety Data

• Hazardous Substances Data: 1541198-39-3(Hazardous Substances Data)

Upstream product

• 154257-85-9 1-(3-bromo-5-chlorophenyl)ethan-1-one 
• 1352062-44-2 C₉H₇BrClF₃O 
• 1541198-37-1 C₁₀H₉BrClF₃O₃S 
• 1541198-38-2 C₁₀H₉BrClF₃ 
• 68-12-2 N,N-dimethyl-formamide 
• 14862-52-3 1,3-dibromo-5-chlorobenzene 

Downstream Products

• 1541199-38-5 (S)-3-amino-3-(3-chloro-5-(1,1,1-trifluoro-2-methylpropan-2-yl)phenyl)propanoic acid 
• 1541199-39-6 (R)-ethyl 3-amino-3-(3-chloro-5-(1,1,1-trifluoro-2-methylpropan-2-yl)phenyl)propanoate 
• 1541199-37-4 (S)-ethyl 3-amino-3-(3-chloro-5-(1,1,1-trifluoro-2-methylpropan-2-yl)phenyl)propanoate hydrochloride 
• 1541199-40-9 (3S)-ethyl 3-(3-chloro-5-(1,1,1-trifluoro-2-methylpropan-2-yl)phenyl)-3-(2-(3-hydroxy-5-((5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino)benzamido)acetamido)propanoate 
• 1541197-38-9 (3S)-3-(3-chloro-5-(1,1,1-trifluoro-2-methylpropan-2-yl)phenyl)-3-(2-(3-hydroxy-5-((5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino)benzamido)acetamido)propanoic acid 
• 1541198-35-9 rac-ethyl 3-amino-3-(3-chloro-5-(1,1,1-trifluoro-2-methylpropan-2-yl)phenyl)propanoate 

Relevant articles and documents

BETA AMINO ACID DERIVATIVES AS INTEGRIN ANTAGONISTS

Disclosed herein are novel pharmaceutical agents which are useful as integrin receptor antagonists that mediate the pathologic processes of angiogenesis and fibrosis and as such are useful in pharmaceutical compositions and in methods for treating conditions mediated by these integrins by inhibiting or antagonizing these integrins. The novel pharmaceutical agents include those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Methods and intermediates useful for making the pharmaceutical agents and methods of using the pharmaceutical agents are also provided.