15456-86-7

Basic information

• Product Name: Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-
• Synonyms: 4-Bromo-6-Hydroxy-3(2H)-Pyridazinone;Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-;3(2H)-Pyridazinone, 4-bromo-6-hydroxy-;4-Bromo-3-hydroxy-6-pyridazinone;4-Bromo-1,2-dihydropyridazine-3,6-dione;Nsc79701
• CAS NO: 15456-86-7
• Molecular Formula: C₄H₃BrN₂O₂
• Molecular Weight: 190.99
• EINECS: 200-001-2
• Mol File: 15456-86-7.mol
• Article Data: 27

Chemical Properties

• Appearance: /
• Density: 1.965 g/cm³
• Refractive Index: 1.59
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7?+-.0.40(Predicted)
• CAS DataBase Reference: Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-(15456-86-7)
• EPA Substance Registry System: Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-(15456-86-7)

Safety Data

• Hazardous Substances Data: 15456-86-7(Hazardous Substances Data)

Usage

General Description

Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-, also known as 4-bromo-1,2-dihydro-3,6-pyridazinedione, is a chemical compound with the molecular formula C4H3BrN2O2. It is a heterocyclic compound that contains a pyridazine ring and a bromine atom. Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro- has potential pharmaceutical applications, including as an intermediate in the synthesis of pharmaceutical drugs. It is also used in organic synthesis and research as a building block to create more complex compounds. It is important to handle this chemical with care, as it may pose health and environmental hazards.

InChI:InChI=1/C4H3BrN2O2/c5-2-1-3(8)6-7-4(2)9/h1H,(H,6,8)(H,7,9)

Upstream product

• 5926-51-2 bromomaleic anhydride 
• 10034-93-2 hydrazinium sulfate 

Downstream Products

• 6082-66-2 3,4,6-trichloropyridazine 
• 910229-65-1 5-bromo-6-oxo-1,6-dihydropyridazin-3-yl 2,4,6-triisopropylbenzenesulfonate 
• 10344-42-0 4-bromo-3,6-dichloro-pyridazine 
• 1003944-29-3 C₄HBrCl₂N₂ 
• 202931-70-2 3,6-dichloro-4-(pyridin-4-yl)pyridazine 
• 943025-98-7 4-bromo-2-{[4-(methyloxy)phenyl]methyl}-6-({[4-(methyloxy)phenyl]methyl}oxy)-3(2H)-pyridazinone 
• 943025-99-8 5-bromo-2-{[4-(methyloxy)phenyl]methyl}-6-({[4-(methyloxy)phenyl]methyl}oxy)-3(2H)-pyridazinone 

Relevant articles and documents

Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones

The present invention relates to methods for treating Neisseria Gonorrhoeae infection which comprises administering to a subject in need thereof novel 1,2-dihydro-2a,5,8a-triazaacenaphthylene-3,8-dione compounds: or pharmaceutically acceptable salts thereof and/or corresponding pharmaceutical compositions.

A general approach to access 5,6-dihydroindolo-naphthyridine ring system

We report a general approach for the synthesis of 5,6-dihydroindolo-naphthyridine ring system via an intramolecular cyclization of the indole NH to an alkene moiety as the key step.

Access to 4-alkylaminopyridazine derivatives via nitrogen-assisted regioselective pd-catalyzed reactions

3-Substituted, 6-substituted, and unsymmetrical 3,6-disubstituted 4-alkylaminopyridazines were prepared from a sequence of three chemo- and regioselective reactions combining amination and palladium-catalyzed cross-coupling reactions, such as reductive dehalogenation and Suzuki-Miyaura reactions. Extension of the methodology to Sonogashira reaction yielded a novel class of 3-substituted pyrrolopyridazines.