154822-27-2

Basic information

• Product Name: 3-hydroxy-7-methoxy-2-phenyl-3-(2-pyridyl)-2,3-dihydro-1H-isoindolin-1-one
• Synonyms: 3-hydroxy-7-methoxy-2-phenyl-3-(2-pyridyl)-2,3-dihydro-1H-isoindolin-1-one
• CAS NO: 154822-27-2
• Molecular Weight: 332.359
• Mol File: 154822-27-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-7-methoxy-2-phenyl-3-(2-pyridyl)-2,3-dihydro-1H-isoindolin-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-7-methoxy-2-phenyl-3-(2-pyridyl)-2,3-dihydro-1H-isoindolin-1-one(154822-27-2)
• EPA Substance Registry System: 3-hydroxy-7-methoxy-2-phenyl-3-(2-pyridyl)-2,3-dihydro-1H-isoindolin-1-one(154822-27-2)

Safety Data

• Hazardous Substances Data: 154822-27-2(Hazardous Substances Data)

Upstream product

• 2459-07-6 methyl pyridine-2-carboxylate 
• 6833-21-2 2-methoxy-N-phenylbenzamide 
• 14805-91-5 N,N-dimethylpicolinamide 

Relevant articles and documents

Application of organolithium and related reagents in synthesis. Part 221. Synthetic strategies based on ortho-aromatic metallation. A concise regiospecific conversion of benzoic acids into the 4-pyridyl-2h-phthalazin- 1-ones

The synthesis of phthalazin-1-ones 6, 7, 8 via the reaction of 3- hydroxyisoindolin-1-ones 3, 4, 5 with hydrazine hydrate is described. Starting compounds 3, 4, 5 were regiospecifically prepared upon the lithiation (n-BuLi) of the benzanilides 1 and subsequently the reaction of the dilithiated anilides 2 with methyl pyridinecarboxylates.