1552300-17-0

Basic information

• Product Name: 2-(trans-4-(3-bromo-6-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methylpyridin-4-ylamino)cyclohexyloxy)ethanol
• Synonyms: 2-(trans-4-(3-bromo-6-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methylpyridin-4-ylamino)cyclohexyloxy)ethanol
• CAS NO: 1552300-17-0
• Molecular Weight: 422.365
• Mol File: 1552300-17-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(trans-4-(3-bromo-6-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methylpyridin-4-ylamino)cyclohexyloxy)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(trans-4-(3-bromo-6-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methylpyridin-4-ylamino)cyclohexyloxy)ethanol(1552300-17-0)
• EPA Substance Registry System: 2-(trans-4-(3-bromo-6-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methylpyridin-4-ylamino)cyclohexyloxy)ethanol(1552300-17-0)

Safety Data

• Hazardous Substances Data: 1552300-17-0(Hazardous Substances Data)

Upstream product

• 1072-53-3 ethyleneglycol sulfate 
• 1552300-16-9 trans-4-(3-bromo-6-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methylpyridin-4-ylamino)cyclohexanol 
• 1541125-83-0 3-bromo-6-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methylpyridine 
• 1552300-15-8 3-bromo-6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-iodo-2-methylpyridine 
• 110-13-4 2,5-hexanedione 

Downstream Products

• 1552300-22-7 (E)-ethyl 3-(6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-(trans-4-(2-hydroxyethoxy)cyclohexylamino)-2-methylpyridin-3-yl)acrylate 
• 1552300-35-2 7-amino-1-(trans-4-(2-hydroxyethoxy)cyclohexyl)-5-methyl-1,6-naphthyridin-2(1H)-one 
• 1552300-41-0 7-amino-3-bromo-1-(trans-4-(2-hydroxyethoxy)cyclohexyl)-5-methyl-1,6-naphthyridin-2(1H)-one 
• 1552300-47-6 7-amino-1-(trans-4-(2-hydroxyethoxy)cyclohexyl)-3-(6-methoxypyridin-3-yl)-5-methyl-1,6-naphthyridin-2(1H)-one 
• 1552300-60-3 N-(5-(7-amino-1-(trans-4-(2-hydroxyethoxy)cyclohexyl)-5-methyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide 

Relevant articles and documents

Identification of novel 7-amino-5-methyl-1,6-naphthyridin-2(1H)-one derivatives as potent PI3K/mTOR dual inhibitors

Inhibition of the phosphoinositide 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway is one of the most intensively studied approaches to cancer therapy. Rational design led to the identification of novel 7-amino-5-methyl-1,6-naph