15535-95-2

Basic information

• Product Name: 4-AMIDINOBENZOIC ACID
• Synonyms: 4-AMIDINOBENZOIC ACID;4-CARBAMIMIDOYL-BENZOIC ACID;4-CARBOXYBENZAMIDINE
• CAS NO: 15535-95-2
• Molecular Formula: C₈H₈N₂O₂
• Molecular Weight: 164.16
• Mol File: 15535-95-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 340.9±44.0 °C(Predicted)
• Appearance: /
• Density: 1.35±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.40±0.10(Predicted)
• CAS DataBase Reference: 4-AMIDINOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMIDINOBENZOIC ACID(15535-95-2)
• EPA Substance Registry System: 4-AMIDINOBENZOIC ACID(15535-95-2)

Safety Data

• Hazardous Substances Data: 15535-95-2(Hazardous Substances Data)

Usage

General Description

4-AMIDINOBENZOIC ACID is a chemical compound with the molecular formula C8H8N2O2. It is a white crystaline solid that is soluble in water. 4-AMIDINOBENZOIC ACID is commonly used in the pharmaceutical industry as a building block in the synthesis of various drugs, particularly antifibrinolytic agents such as tranexamic acid. It is also used as a pH indicator, particularly in the determination of zinc. Additionally, 4-AMIDINOBENZOIC ACID has been studied for its potential use as an antimicrobial agent due to its ability to inhibit the growth of certain bacteria and fungi. However, further research is needed to fully understand its antimicrobial properties and potential applications.

Upstream product

• 42823-72-3 4-(aminoiminomethyl)benzoic acid hydrochloride 
• 5418-97-3 4-amidino-benzoic acid ethyl ester hydrochloride 

Downstream Products

• 153074-91-0 N-tert-butoxycarbonyl-4-amidinobenzoic acid 
• 147290-45-7 4-benzoic acid 
• 144412-48-6 {1-[(S)-2-(4-Carbamimidoyl-benzoylamino)-propionyl]-piperidin-4-yloxy}-acetic acid tert-butyl ester 
• 144412-18-0 Ro 44-3888 
• 138108-45-9 N-<3-(benzyloxycarbonyl)-N-<5-benzamido>valeryl>-L-alanyl>-3-phenyl-L-alanine benzyl ester 
• 1025838-55-4 (S)-N-((S)-1-Benzyloxycarbonyl-2-phenyl-ethyl)-3-[5-(4-carbamimidoyl-benzoylamino)-pentanoylamino]-succinamic acid benzyl ester 
• 138108-61-9 benzyl (S)-3-<benzoyl>-β-alanyl>amino>-3-<(p-methoxyphenethyl)carbamoyl>propionate 
• 138109-27-0 N-[N-[N-(p-amidinobenzoyl)-β-alanyl]-3-(t-butoxycarbonyl)-L-alanyl]-3-(p-t-butoxyphenyl)-L-alanine t-butyl ester 
• 146118-12-9 t-butyl [[1-[N₂-(p-amidinobenzoyl)-N₅-(t-butoxycarbonyl)-L-ornithyl]-4-piperidinyl]oxy]acetate 
• 135321-58-3 N-amidino>benzamido>benzoyl>-β-alanine benzyl ester 
• 144412-02-2 N-[N-[p-[N-(benzyloxycarbonyl)amidino]benzoyl]-β-alanyl]-β-alanine benzylester 
• 178601-17-7 (S)-<<1-<2-<4-<(aminoiminomethyl)benzoyl>amino>-3-(4-hydroxyphenyl)propionyl>piperidin-4-yl>oxy>acetic acid tert-butyl ester 
• 144412-49-7 lamifiban 

Relevant articles and documents

Monolayer nanosheets formed by liquid exfoliation of charge-assisted hydrogen-bonded frameworks

Hydrogen-bonded organic frameworks (HOFs) are a diverse and tunable class of materials, but their potential as free-standing two-dimensional nanomaterials has yet to be explored. Here we report the self-assembly of two layered hydrogen-bonded frameworks based on strong, charge-assisted hydrogen-bonding between carboxylate and amidinium groups. Ultrasound-assisted liquid exfoliation of both materials readily produces monolayer hydrogen-bonded organic nanosheets (HONs) with micron-sized lateral dimensions. The HONs show remarkable stability and maintain their extended crystallinity and monolayer structures even after being suspended in water at 80 °C for three days. These systems also exhibit efficient fluorescence quenching of an organic dye in organic solvents, superior to the quenching ability of the bulk frameworks. We anticipate that this approach will provide a route towards a diverse new family of molecular two-dimensional materials.

NOVEL ETHYLENEDIAMINE DERIVATIVES

A compound represented by the following formula (1):Q-Q-T-N(R)-Q-N(R)-T-Q [wherein, R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6- membered cyclic hydrocarbon group which may have a substituent, or the like; Q2 is a single bond or the like; Q3 represents the following group: -C(R3a)(R4a)-{C(R3b)(R4b)}m1-{C(R3c)(R4c)}m2-{C(R3d)(R4d)}m3-{C(R3e)(R4e)}m4-C(R3f)(R4f)- (in which, R3a to R4e represent hydrogen or the like); T0 represents a carbonyl group or the like; and T1 represents -COCONR- or the like]; or salt thereof, solvate thereof, or N-oxide thereof. The compound is useful as a preventive and/or therapeutic agent for cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.