155486-89-8

Basic information

• Product Name: (-)-(4aS,6R,8aS)-3,4,4a,5,6,7,8,8a-octahydro-6-benzyloxy-5,5,8a-trimethyl-1(2H)-naphthalenone
• Synonyms: (-)-(4aS,6R,8aS)-3,4,4a,5,6,7,8,8a-octahydro-6-benzyloxy-5,5,8a-trimethyl-1(2H)-naphthalenone
• CAS NO: 155486-89-8
• Molecular Weight: 300.441
• Mol File: 155486-89-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-(4aS,6R,8aS)-3,4,4a,5,6,7,8,8a-octahydro-6-benzyloxy-5,5,8a-trimethyl-1(2H)-naphthalenone(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(4aS,6R,8aS)-3,4,4a,5,6,7,8,8a-octahydro-6-benzyloxy-5,5,8a-trimethyl-1(2H)-naphthalenone(155486-89-8)
• EPA Substance Registry System: (-)-(4aS,6R,8aS)-3,4,4a,5,6,7,8,8a-octahydro-6-benzyloxy-5,5,8a-trimethyl-1(2H)-naphthalenone(155486-89-8)

Safety Data

• Hazardous Substances Data: 155486-89-8(Hazardous Substances Data)

Upstream product

• 155486-87-6 (+)-(4aR,6S,8aR)-3,4,4a,5,6,7,8,8a-octahydro-6-hydroxy-5,5,8a-trimethyl-1(2H)-naphthalenone 1-ethylene ketal 
• 155393-00-3 (-)-(4aS,6R,8aS)-3.4,4a,5,6,7,8,8a-octahydro-6-benzyloxy-5,5,8a-trimethyl-1(2H)-naphthalenone 1-ethylene ketal 
• 100-39-0 benzyl bromide 

Downstream Products

• 155392-87-3 (3aS,5R,7aS)-octahydro-5-benzyloxy-1-formyl(hydroxy)methylene-4,4,7a-trimethyl-1H-indene 
• 155392-85-1 (-)-(4aS,6R,8aS)-4a,5,6,7,8,8a-hexahydro-6-benzyloxy-2-methoxy-5,5,8a-trimethyl-1(4H)-naphthalenone 
• 155392-84-0 (-)-(4aS,6R,8aS)-4a,5,6,7,8,8a-hexahydro-6-benzyloxy-2-hydroxy-5,5,8a-trimethyl-1(4H)-naphthalenone 
• 541501-19-3 C₃₉H₄₉BrO₅Si 
• 614719-21-0 [1'⁽²⁾R,2'R,4'aS,6'R,8'aS]-4-benzyloxy-7-ethenyl-6'-hydroxy-3',4',4'a,5',6',7',8',8'a-octahydro-2',5',5',8'a-tetramethylspiro[benzofuran-2(3H),1'(2'H)-naphthalene]-6-carboxylic acid methyl ester 
• 614719-22-1 [1'⁽²⁾R,2'R,4'aS,6'R,8'aS]-4-benzyloxy-7-formyl-6'-hydroxy-3',4',4'a,5',6',7',8',8'a-octahydro-2',5',5',8'a-tetramethylspiro[benzofuran-2(3H),1'(2'H)-naphthalene]-6-carboxylic acid methyl ester 
• 614719-20-9 [2R,4aS,6R,8aS]-6-benzyloxy-2,5,5,8a-tetramethyloctahydronaphthalen-1-ylidenehydrazine 
• 541501-16-0 [1'⁽²⁾R,2'R,4'aS,6'R,8'aS]-4-(tert-butyldiphenylsilyloxy)-6'-hydroxy-3',4',4'a,5',6',7',8',8'a-octahydro-2',5',5',8'a-tetramethylspiro[benzofuran-2(3H),1'(2'H)-naphthalene]-6-carboxylic acid methyl ester 
• 541501-18-2 [1'⁽²⁾R,2'R,4'aS,6'R,8'aS]-6'-hydroxy-7-cyano-3',4',4'a,5',6',7',8',8'a-octahydro-2',5',5',8'a-tetramethylspiro[benzofuran-2(3H),1'(2'H)-naphthalene]-6-carboxylic acid methyl ester 
• 541501-15-9 [1'⁽²⁾R,2'R,4'aS,6'R,8'aS]-4-benzyloxy-5-cyano-6'-hydroxy-3',4',4'a,5',6',7',8',8'a-octahydro-2',5',5',8'a-tetramethyspiro[benzofuran-2(3H),1'(2'H)-naphthalene]-6-carboxylic acid methyl ester 
• 541501-17-1 [1'⁽²⁾R,2'R,4'aS,6'R,8'aS]-4-benzyloxy-7-bromo-6'-hydroxy-3',4',4'a,5',6',7',8',8'a-octahydro-2',5',5',8'a-tetramethylspiro[benzofuran-2(3H),1'(2'H)-naphthalene]-6-carboxylic acid methyl ester 
• 541501-14-8 [1'⁽²⁾R,2'R,4'aS,6'R,8'aS]-4-benzyloxy-5-bromo-6'-hydroxy-3',4',4'a,5',6',7',8',8'a-octahydro-2',5',5',8'a-tetramethylspiro[benzofuran-2(3H),1'(2'H)-naphthalene]-6-carboxylic acid methyl ester 
• 541501-09-1 [2R,4aS,6R,8aS]-4-(6-benzyloxy-2,5,5,8a-tetramethyldecahydronaphthalen-1-ylmethyl)-3,5-dihydroxybenzoic acid methyl ester 

Relevant articles and documents

Synthesis of manool-related labdane diterpenes as platelet aggregation inhibitors

Enantioselective total synthesis of the labdane diterpene (-)-1, was achieved starting from the R-(-)-enantiomer of the Wieland-Miescher ketone (3). The enantiomer (+)-1 was obtained by partial synthesis via microbial transformation of sclareol (24). These results established that the natural compound (+)-1, a platelet aggregation inhibitor, has a normal absolute stereochemistry like that of manool (2). The B-norlabdane-related compound 44 was also synthesized using a novel ring contraction reaction.