155849-49-3 Usage
Description
4-(Trifluoromethyl)piperidine hydrochloride is an organic compound with the chemical formula C6H11F3N·HCl. It is a derivative of piperidine, a heterocyclic amine, featuring a trifluoromethyl group at the 4-position and a hydrochloride counterion. 4-(Trifluoromethyl)piperidine hydrochloride is a key intermediate in the synthesis of various pharmaceuticals and has significant applications in the pharmaceutical industry due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
4-(Trifluoromethyl)piperidine hydrochloride is used as a key intermediate in the synthesis of adenosine receptor antagonists for the treatment of various conditions, including asthma, chronic obstructive pulmonary disease (COPD), and other respiratory disorders. Its incorporation into these antagonists helps modulate the activity of adenosine receptors, which play a crucial role in regulating bronchoconstriction and inflammation.
Additionally, 4-(Trifluoromethyl)piperidine hydrochloride may also be utilized in the development of other therapeutic agents targeting different receptors or enzymes in the pharmaceutical industry. Its unique structural features and reactivity make it a valuable building block for the creation of novel drugs with potential applications in various therapeutic areas.
Check Digit Verification of cas no
The CAS Registry Mumber 155849-49-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,8,4 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 155849-49:
(8*1)+(7*5)+(6*5)+(5*8)+(4*4)+(3*9)+(2*4)+(1*9)=173
173 % 10 = 3
So 155849-49-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H10F3N.ClH/c7-6(8,9)5-1-3-10-4-2-5;/h5,10H,1-4H2;1H
155849-49-3Relevant articles and documents
PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE
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Page/Page column 19, (2008/06/13)
The present invention relates to the compound represented by formula (I) (wherein R1 and R2 is hydrogen atom, C1-8 alkyl etc.; R3 is C1-8 alkyl which may be substituted with 1 to 3 halogen atom(s), phenyl; R4 is hydrogen atom etc. ; R5 and R6 is hydrogen atom, CI-8 alkyl etc.; X is sulfur atom or oxygen atom etc.; ringA is cyclic group which may have a substituent(s).), or a salt thereof Toxicity of the compound represented by formula (I) is very low, and it is safe enough to use as a pharmaceutical agent and since it has PPAR δ agonistic activity, it is useful as preventive and/or therapeutic agent for glucose lipid metabolic disorder, hypertension, circulatory diseases etc.
