1560-54-9Relevant articles and documents
Supramolecular Recognition of Quaternary Phosphonium Cations
Walsh, Mark P.,Kitching, Matthew O.
, (2021/12/06)
The modes of supramolecular recognition of quaternary phosphonium cations mediated by 1,1′-bi-2-naphthol (BINOL) are identified and characterized. In contrast to our previous work on ammonium cations, the recognition of the quaternary phosphonium cations via the formation of a PR4+·Br–·BINOL ternary complex was found to be mediated by a hydrogen bond from an α-carbon center of the phosphonium cation, encapsulation within a continuous hydrogen bond network between the halide–BINOL network, or a combination of these effects working in tandem. The solid state structures of these ternary complexes were analyzed by X-ray crystallography, aided by Hirshfeld surface analysis, to confirm the presence of characteristic intermolecular interactions for the identified modes. In all cases, the quaternary phosphonium cation acts as a hydrogen bond donor (HBD) in these supramolecular interactions, and thus this is the key to the recognition process with BINOL. The characterization of such mechanisms offers insight into the supramolecular and crystal engineering communities in the future design of agents capable of the supramolecular recognition of phosphonium cations and their abstraction from the solution phase.
Cascade 8πElectrocyclization/Benzannulation to Access Highly Substituted Phenylpyridines
Du, Luan,Gong, Yiliang,Han, Jingpeng,Li, Baosheng,Li, You,Luo, Han,Tian, Yi,Xin, Xiaolan
supporting information, p. 7966 - 7971 (2021/10/25)
A cascade 8πelectrocyclization/benzannulation reaction was developed to obtain the synthetically important highly substituted phenyl-pyridines. This method shows great potential in the rapid and inexpensive application of the scalable and operationally simple production of accessible substrates. On the basis of the resulting phenyl-pyridine products, a new Ru catalyst and bidentate ligand were designed and prepared, further demonstrating its high practicability.
Radical-Mediated Heck-Type Alkylation: Stereoconvergent Synthesis of Functionalized Polyenes
Zhang, Hong,Wu, Xinxin,Wei, Yunlong,Zhu, Chen
supporting information, p. 7568 - 7572 (2019/10/02)
The stereospecific synthesis of polyenes is of great synthetic value. Disclosed herein is a new, efficient, stereoconvergent approach for the synthesis of functionalized polyenes via a radical-mediated Heck-type alkylation. The easily accessed Z- and E-mixed alkenes are harnessed as starting material, leading to a unique stereoisomer of polyenes. In addition, the transformation features mild reaction conditions and broad functional group compatibility. A variety of valuable 1,3-dienes and 1,3,5-trienes are afforded in useful yields.
