156335-37-4

Basic information

• Product Name: Ethyl 4-oxo-1,4-dihydropy...
• Synonyms: Ethyl 4-oxo-1,4-dihydropy...;Ethyl 4-oxo-1,4-dihydropyrrolo[1,2-b]pyridazine-3-carboxylate;Pyrrolo[1,2-b]pyridazine-3-carboxylic acid, 1,4-dihydro-4-oxo-, ethyl ester;ethyl 4-oxo-1H,4H-pyrrolo[1,2-b]pyridazine-3-carboxylate;ethyl 1,4-dihydro-4-oxopyrrolo[1,2-b]pyridazine-3-carboxylate
• CAS NO: 156335-37-4
• Molecular Formula: C₁₀H₁₀N₂O₃
• Molecular Weight: 206.198
• Mol File: 156335-37-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 332.446°C at 760 mmHg
• Flash Point: 154.858°C
• Appearance: /
• Density: 1.354g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.619
• CAS DataBase Reference: Ethyl 4-oxo-1,4-dihydropy...(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 4-oxo-1,4-dihydropy...(156335-37-4)
• EPA Substance Registry System: Ethyl 4-oxo-1,4-dihydropy...(156335-37-4)

Safety Data

• Hazardous Substances Data: 156335-37-4(Hazardous Substances Data)

Usage

General Description

Ethyl 4-oxo-1,4-dihydropy is a chemical compound with the molecular formula C6H8O2. It is a heterocyclic compound that contains a pyran ring, a six-membered heterocyclic ring with oxygen as a heteroatom. Ethyl 4-oxo-1,4-dihydropy... is widely used in the pharmaceutical industry for the synthesis of various drugs and experimental research. It is also a versatile building block in the field of organic synthesis, particularly in the preparation of various fine chemicals and biologically active compounds. Due to its reactivity and functional groups, ethyl 4-oxo-1,4-dihydropy is of great interest to chemists and researchers for the development of new compounds with potential pharmacological properties.

InChI:InChI=1/C10H10N2O3/c1-2-15-10(14)7-6-11-12-5-3-4-8(12)9(7)13/h3-6,11H,2H2,1H3

Upstream product

• 765-39-9 1H-pyrrol-1-amine 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 156335-36-3 diethyl (1-pyrrolyl)aminomethylenepropanedioate 

Downstream Products

• 156335-30-7 1,4-dihydro-4-oxopyrrolo<1,2-b>pyridazine-3-carboxylic acid 
• 888720-26-1 pyrrolo[1,2-b]pyridazin-4(1H)-one 
• 1187875-95-1 4-(4-nitrophenoxy)-pyrrolo[1,2-b]pyridazine 
• 1187875-97-3 4-(pyrrolo[1,2-b]pyridazin-4-yloxy)benzenamine 
• 1221713-71-8 N-(3-fluoro-4-(5-phenylpyrrolo[1,2-b]pyridazin-4-yloxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide 
• 1221714-55-1 1-(4-(2-fluoro-4-nitrophenoxy)pyrrolo[1,2-b]pyridazin-5-yl)ethanone 
• 1221714-45-9 4-(5-bromopyrrolo[1,2-b]pyridazin-4-yloxy)-3-fluoroaniline 
• 1221714-44-8 5-bromo-4-(2-fluoro-4-nitrophenoxy)pyrrolo[1,2-b]pyridazine 
• 888720-27-2 4-(2-fluoro-4-nitrophenoxy)pyrrolo[1,2-b]pyridazine 
• 1221713-69-4 N-(4-(5-bromopyrrolo[1,2-b]pyridazin-4-yloxy)-3-fluorophenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide 
• 156335-40-9 4-ethoxypyrrolo<1,2-b>pyridazine-3-carboxylic acid 

Relevant articles and documents

CONDENSED HETEROCYCLIC COMPOUND

Provided is a compound represented by the following formula, or a salt thereof: [wherein each symbol is as defined herein.].

AURORA KINASE MODULATORS AND METHOD OF USE

The present invention relates to chemical compounds having a general formula (I) wherein A1-5 and 7-8, D', L1, L2, R1, R3, R6-8, n and o are defined herein, and synthetic intermediates, which are capable of modulating the activity of Aurora kinase proteins and, thereby, influencing various disease states and conditions related to the activities of Aurora kinases. For example, the compounds are capable of influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of Aurora kinase.