156453-53-1

Basic information

• Product Name: (R)-α-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol
• Synonyms: (R)-α-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol;(R)-3-(Naphthalen-1-yloxy)-1-phenylpropan-1-ol;(R)-a-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol
• CAS NO: 156453-53-1
• Molecular Formula: C19H18O2
• Molecular Weight: 278.34502
• EINECS: -0
• Mol File: 156453-53-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 474.0±33.0 °C(Predicted)
• Appearance: /
• Density: 1.162±0.06 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
• PKA: 14.00±0.20(Predicted)
• CAS DataBase Reference: (R)-α-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-α-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol(156453-53-1)
• EPA Substance Registry System: (R)-α-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol(156453-53-1)

Safety Data

• Hazardous Substances Data: 156453-53-1(Hazardous Substances Data)

Usage

Description

(R)-α-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol, also known as (αR)-α-[2-(1-Naphthalenyloxy)ethyl]benzenemethanol, is an organic compound with a complex molecular structure. It is characterized by its naphthalenyloxyethyl and benzeneMethanol functional groups, which contribute to its unique chemical properties. (R)-α-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol is primarily recognized as an impurity in the pharmaceutical compound Dapoxetine (D185700), a Selective serotonin reuptake inhibitor (SSRI).

Uses

Used in Pharmaceutical Industry:
(R)-α-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol is used as an impurity in the production of Dapoxetine (D185700), a Selective serotonin reuptake inhibitor (SSRI). Its presence in the manufacturing process of Dapoxetine is significant, as it can impact the overall quality, efficacy, and safety of the final product. The pharmaceutical industry must carefully monitor and control the levels of this impurity to ensure the therapeutic benefits of Dapoxetine are not compromised.
In the context of Dapoxetine, (R)-α-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol serves as a critical reference point for quality control and regulatory compliance. By understanding its role as an impurity, researchers and manufacturers can develop strategies to minimize its presence, thereby enhancing the purity and effectiveness of Dapoxetine as a treatment for various conditions related to serotonin regulation.