1564624-36-7

Basic information

• Product Name: Methyl 3-bromo-4-fluoro-6-methylbenzoate
• Synonyms: Methyl 3-bromo-4-fluoro-6-methylbenzoate;METHYL 5-BROMO-4-FLUORO-2-METHYLBENZOATE
• CAS NO: 1564624-36-7
• Molecular Formula: C9H8BrFO2
• Molecular Weight: 247.0610232
• EINECS: -0
• Mol File: 1564624-36-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 260.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.506±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl 3-bromo-4-fluoro-6-methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-bromo-4-fluoro-6-methylbenzoate(1564624-36-7)
• EPA Substance Registry System: Methyl 3-bromo-4-fluoro-6-methylbenzoate(1564624-36-7)

Safety Data

• Hazardous Substances Data: 1564624-36-7(Hazardous Substances Data)

Usage

General Description

Methyl 3-bromo-4-fluoro-6-methylbenzoate is a chemical compound with the molecular formula C9H8BrFO2. It is a derivative of benzoic acid, containing a methyl ester group at the 3 position, a bromine atom at the 4 position, and a fluorine atom at the 6 position of the benzene ring. Methyl 3-bromo-4-fluoro-6-methylbenzoate is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active compounds. It is also known for its potential applications in the development of agrochemicals and material science. Additionally, due to the presence of bromine and fluorine atoms, it may exhibit specific chemical reactivity and properties that make it suitable for specialized uses in the field of chemistry.

Upstream product

• 321-21-1 4-fluoro-2-methylbenzoic acid 
• 1427416-33-8 5-bromo-4-fluoro-2-methylbenzoic acid 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 

Relevant articles and documents

ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF

Compounds of formula (I) useful as inhibitors of ADAMTS-5 and/or ADAMTS-4, pharmaceutical compositions thereof, and use of them as therapeutic agents for the treatment of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis, are disclosed.

APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS AND METHODS OF USE THEREOF

The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts and esters thereof: which inhibit the Apoptosis signal-regulating kinase 1 (ASK-1), which associated with autoimmune disorders, neurodegenerative disorders, inflammatory diseases, chronic kidney disease, cardiovascular disease. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from ASK-1 related disease. The invention also relates to methods of treating an ASK-1 related disease in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention specifically relates to methods of treating ASK-1 associated with hepatic steatosis, including non-alcoholic fatty liver disease (NAFLD) and non-alcohol steatohepatitis disease (NASH).