156481-74-2

Basic information

• Product Name: (R)-4,5,5-TRIPHENYL-2-OXAZOLIDINONE
• Synonyms: (R)-(+)-4,5,5-TRIPHENYL-2-OXAZOLIDINONE;(R)-4,5,5-TRIPHENYL-2-OXAZOLIDINONE;(R)-4,5,5-Triphenyloxazolidin-2-one;(R)-4,5,5-Triphenyl-2-oxazolidinone, ee: 97%;(R)-4,5,5-Triphenyloxazolidin-2-one,99%e.e.;(R)-4,5,5-Triphenyl-2-oxazolidinone, 97%, ee: 97%
• CAS NO: 156481-74-2
• Molecular Formula: C₂₁H₁₇NO₂
• Molecular Weight: 315.37
• Mol File: 156481-74-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 246-250 °C(lit.)
• Boiling Point: 513 °C at 760 mmHg
• Flash Point: 264.1 °C
• Appearance: /
• Density: 1.197 g/cm³
• Vapor Pressure: 1.23E-10mmHg at 25°C
• Refractive Index: 1.617
• PKA: 11.07±0.60(Predicted)
• CAS DataBase Reference: (R)-4,5,5-TRIPHENYL-2-OXAZOLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4,5,5-TRIPHENYL-2-OXAZOLIDINONE(156481-74-2)
• EPA Substance Registry System: (R)-4,5,5-TRIPHENYL-2-OXAZOLIDINONE(156481-74-2)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 156481-74-2(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C21H17NO2/c23-20-22-19(16-10-4-1-5-11-16)21(24-20,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15,19H,(H,22,23)/t19-/m1/s1

Upstream product

• 62183-23-7 4,5,5-triphenyl-oxazolidin-2-one 
• 141190-94-5 (R)-N-(tert-butoxycarbonyl)phenylglycine methyl ester 
• 19883-41-1 D-phenylglycine methyl ester hydrochloride 
• 875-74-1 (R)-phenylglycine 
• 223906-34-1 (2R)-N-Boc-2-amino-1,1,2-triphenylpropanol 
• 60539-17-5 (R)-(+)-2-amino-1,1,2-triphenylethanol 
• 503-38-8 trichloromethyl chloroformate 

Downstream Products

• 223906-51-2 (4R)-N-Propionyl-4,5,5-triphenyloxazolidin-2-one 
• 1393834-04-2 (2'S,4R,Z)-3-(4'-benzyloxyl-2'-benzylbut-3'-enoyl)-4,5,5-triphenyloxazolidinone 
• 1393834-00-8 (2'R,4R,Z)-3-(4'-benzyloxyl-2'-benzylbut-3'-enoyl)-4,5,5-triphenyloxazolidinone 
• 1393833-98-1 (2'R,4R,Z)-3-(4'-benzyloxyl-2'-allylbut-3'-enoyl)-4,5,5-triphenyloxazolidinone 
• 1393834-03-1 (2'S,4R,Z)-3-(4'-benzyloxyl-2'-allylbut-3'-enoyl)-4,5,5-triphenyloxazolidinone 
• 1393834-02-0 (2'S,4R,Z)-N-(4'-benzyloxyl-2-methylbut-3'-enoyl)-4,5,5-triphenyloxazolidin-2-one 
• 1393834-15-5 (4R,Z)-N-(4'-benzyloxy-but-3'-enoyl)-4,5,5-triphenyloxazolidin-2-one 
• 1215291-30-7 (R)-4,5,5-triphenyl-3-[(E)-3-phenylprop-2-enoyl]oxazolidin-2-one 
• 1215291-27-2 (R)-3-[(E)-but-2-enoyl]-4,5,5-triphenyloxazolidin-2-one 
• 156481-81-1 (R)-3-((1R,2S)-2-Fluoro-cyclopropyl)-4,5,5-triphenyl-oxazolidin-2-one 
• 156481-77-5 (4R)-4,5,5-triphenyl-3-vinyl-2-oxazolidinone 

Relevant articles and documents

Synthesis and application of N-3,5-dinitrobenzoyl and C3 symmetric diastereomeric chiral stationary phases

Three diastereomeric chiral compounds, namely, (R,R)-(+)-2-amino-1,2-diphenylethanol, (1S,2R)-(+)-2-amino-1,2-diphenylethanol, and (1R,2R)-(+)-1,2-diphenylethylenediamine were used as starting materials for preparing three N-3,5-dinitrobenzoyl derivative

Remarkably efficient charcoal-promoted ring-closing carbonylations

An efficient, versatile and practical gram-scale preparation of oxazolidinone, imidazolidinone and dioxolanone is achieved. Georg Thieme Verlag Stuttgart.

Synthetic Studies on the Key Component of the New Generation of Quinolonecarboxylic Acid, DU-6859. 2. Asymmetric Synthesis of (1R,2S)-2-Fluorocyclopropylamine

The title synthesis was achieved by featuring diastereoface-selective cyclopropanation of (4R,5S)-4,5-diphenyl-3-vinyl-2-oxazolidinone and its related compounds, the chiral conformationally rigid N-vinylcarbamates, with zinc-monofluorocarbenoid, followed