157001-18-8

Basic information

• Product Name: 1-((E)-3,3-Diethoxy-propenyl)-2-methoxy-benzene
• Synonyms: 1-((E)-3,3-Diethoxy-propenyl)-2-methoxy-benzene
• CAS NO: 157001-18-8
• Molecular Weight: 236.311
• Mol File: 157001-18-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-((E)-3,3-Diethoxy-propenyl)-2-methoxy-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-((E)-3,3-Diethoxy-propenyl)-2-methoxy-benzene(157001-18-8)
• EPA Substance Registry System: 1-((E)-3,3-Diethoxy-propenyl)-2-methoxy-benzene(157001-18-8)

Safety Data

• Hazardous Substances Data: 157001-18-8(Hazardous Substances Data)

Upstream product

• 3054-95-3 acrylaldehyde diethyl acetal 
• 529-28-2 4-iodoanisol 

Downstream Products

• 60125-24-8 (E)-3-(2-methoxyphenyl)propenal 

Relevant articles and documents

An efficient palladium-catalyzed synthesis of cinnamaldehydes from acrolein diethyl acetal and aryl iodides and bromides

(Matrix presented) The reaction of aryl iodides and bromides with acrolein diethyl acetal in the presence of Pd(OAc)2, nBu 4NOAc, K2CO3, KCl, and DMF, at 90°C until the disappearance of the acetal followed by the addition of 2 N HCl to the crude reaction mixture, affords cinnamaldehydes in good to high yields. A variety of functional groups are tolerated in the aryl halides, including ether, aldehyde, ketone, ester, dialkylamino, nitrile, and nitro groups. The presence of substituents close to the oxidative addition site does not hamper the reaction.