1571918-48-3Relevant articles and documents
Aziridine ring opening for the synthesis of sphingolipid analogues: Inhibitors of sphingolipid-metabolizing enzymes
Alcaide, Anna,Llebaria, Amadeu
, p. 2993 - 3029 (2014/05/06)
A library of sphingolipid analogues is designed and tested as inhibitors against mammalian and fungal sphingolipid enzymes. The synthesis of sphingolipid analogues is based on the nucleophilic ring-opening reactions of N-activated aziridine derivatives wi