1575-94-6Relevant articles and documents
A simple and one-pot multi-component reaction to the synthesis of methylenebisamides
Mohammadi, Bagher,Khorrami, Bahareh Rezaei
, p. 1089 - 1092 (2018)
Abstract: This work described a simple and efficient method for the synthesis of some methylenebisamide derivatives. The reaction is carried out via a simple multi-component reaction between arylaldehydes, DMSO, and hydroxylamine hydrochloride. Short reaction times, excellent yields of products, inexpensive and readily available starting material, eco-friendly method, easy work-up, and high atom economy are the main advantages of this reaction.
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Gradsten,Pollock
, p. 3079 (1948)
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Cobalt(III)-Catalyzed and Dimethyl Sulfoxide-Involved Cross-Coupling of Ketones and Amides for Direct Synthesis of β-Amino Ketones
Xu, Xuefeng,Zhou, Zhi,Wang, Zhipin,Ma, Xinna,Chen, Xin,Zhang, Xu,Yu, Xiyong,Yi, Wei
supporting information, p. 4278 - 4285 (2019/08/12)
A straightforward synthesis of β-amino ketones has been realized by employing ketones and amides as the substrates via cobalt(III)-catalyzed and dimethyl sulfoxide-involved cross-coupling reaction. Experimental investigations revealed that the β-methylsul
Selectfluor-mediated oxidative methylenation of amide with N, N -dimethylpropanamide for N, N ′-methylenebisamide synthesis
Cao, Yue,Zhou, Dongheng,Ma, Yongmin
, p. 37 - 41 (2019/01/10)
A simple and efficient approach for the synthesis of N,N′-methylenebisamides through a Selectfluor-mediated oxidative reaction of aromatic amides and N,N-dimethylpropanamide (DMP) is described. Remarkable results clearly reveal that DMP plays a dual role in this reaction, as both a one-carbon source and an environment-friendly solvent. Moreover, the process provides new strategies for the synthesis of bisamides with advantages of operationally simple, insensitive to atmospheric conditions, and good to high yields.