1578-14-9

Basic information

• Product Name: 3-bromosenecioic acid
• Synonyms: 3-bromosenecioic acid
• CAS NO: 1578-14-9
• Molecular Formula: C₅H₇BrO₂
• Molecular Weight: 179.0119
• Mol File: 1578-14-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 257.2 °C at 760 mmHg
• Flash Point: 109.4 °C
• Appearance: /
• Density: 1.596 g/cm³
• Vapor Pressure: 0.0247mmHg at 25°C
• Refractive Index: 1.491
• CAS DataBase Reference: 3-bromosenecioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromosenecioic acid(1578-14-9)
• EPA Substance Registry System: 3-bromosenecioic acid(1578-14-9)

Safety Data

• Hazardous Substances Data: 1578-14-9(Hazardous Substances Data)

Usage

General Description

3-bromosenecioic acid is a chemical compound that is a derivative of senecioic acid, a natural product found in certain plants. It has a molecular formula of C9H11BrO4 and a molecular weight of 266.09 g/mol. 3-bromosenecioic acid is a brominated derivative of senecioic acid, which is a known hepatotoxic compound and has been linked to liver damage in livestock. 3-bromosenecioic acid may have similar toxicological properties and should be handled with caution. It is important to use proper safety measures when working with this compound and to avoid exposure to skin, eyes, and inhalation.

InChI:InChI=1/C5H9BrO2/c1-5(2,6)3-4(7)8/h3H2,1-2H3,(H,7,8)

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• 40052-24-2 7c-tert-butoxycarbonylamino-2,2-dimethyl-8-oxo-(6rH)-4-thia-1-aza-bicyclo[4.2.0]octane-3t-carboxylic acid benzyl ester 
• 40052-24-2 7c-tert-butoxycarbonylamino-2,2-dimethyl-8-oxo-(6rH)-4-thia-1-aza-bicyclo[4.2.0]octane-3c-carboxylic acid benzyl ester 

Relevant articles and documents

Synthesis of Strained γ-Lactams by Palladium(0)-Catalyzed C(sp3)-H Alkenylation and Application to Alkaloid Synthesis

A variety of strained α-alkylidene-γ-lactams were synthesized by palladium(0)-catalyzed intramolecular C(sp3)-H alkenylation from easily accessible acyclic and monocyclic bromoalkene precursors. These lactams are valuable intermediates for acce

α-Bromoacrylic Acids as C1 Insertion Units for Palladium-Catalyzed Decarboxylative Synthesis of Diverse Dibenzofulvenes

Herein α-bromoacrylic acids have been employed as C1 insertion units to achieve the palladium-catalyzed [4 + 1] annulation of 2-iodobiphenyls, which provides an efficient platform for the construction of diverse dibenzofulvenes. This protocol enables the formation of double C(aryl)-C(vinyl) bonds via a C(vinyl)-Br bond cleavage and decarboxylation. It is particularly noteworthy that the method features a broad substrate scope, and various interesting frameworks, such as bridged ring, fused (hetero)aromatic ring, and divinylbenzene, can be successfully incorporated into the products.

Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via β,γ-unsaturated α-bromo-ketene/imine cycloaddition

An approach to 3-bromo-4-alkyl-6-aryl-5,6-dihydropyridin-2-ones and 3-bromo-5-ethyl-6-aryl-5,6-dihydropyridin-2-ones starting from β,γ-unsaturated α-bromoketenes and imines is reported. The presence of a bromine atom on the double bond allows performing aziridination or bromine displacement with an amine. The reaction gave fused bicyclic N-allyl-aziridines or 3-amino-substituted 5,6-dihydropyridin-2-ones, depending on the substituents on the six-membered ring.