1582316-69-5

Basic information

• Product Name: 2-bromo-N-(but-3-en-1-yl)-N-(2-morpholinophenyl)benzenesulfonamide
• Synonyms: 2-bromo-N-(but-3-en-1-yl)-N-(2-morpholinophenyl)benzenesulfonamide
• CAS NO: 1582316-69-5
• Molecular Weight: 451.384
• Mol File: 1582316-69-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-bromo-N-(but-3-en-1-yl)-N-(2-morpholinophenyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-N-(but-3-en-1-yl)-N-(2-morpholinophenyl)benzenesulfonamide(1582316-69-5)
• EPA Substance Registry System: 2-bromo-N-(but-3-en-1-yl)-N-(2-morpholinophenyl)benzenesulfonamide(1582316-69-5)

Safety Data

• Hazardous Substances Data: 1582316-69-5(Hazardous Substances Data)

Upstream product

• 5585-33-1 2-morpholinoaniline 
• 2905-25-1 o-bromobenzenesulfonyl chloride 
• 627-27-0 homoalylic alcohol 
• 1286918-84-0 C₁₆H₁₇BrN₂O₃S 

Downstream Products

• 1582316-76-4 5-methylene-2-(2-morpholinophenyl)-2,3,4,5-tetrahydrobenzo[f][1,2]thiazepine 1,1-dioxide 
• 1582316-83-3 2-(2-morpholinophenyl)-3'-phenyl-3,4-dihydro-2H,4'H-spiro[benzo[f][1,2]thiazepine-5,5'-isoxazole] 1,1-dioxide 

Relevant articles and documents

Benzonitrile oxide cycloadditions with exocyclic methylene benzothiazepine dioxides

N-substituted 5-methylene-2,3,4,5-tetrahydrobenzo[f][1,2]thiazepine 1,1-dioxides underwent 1,3-dipolar cycloaddition with benzonitrile oxide, generated in situ, to give isoxazoline spiro adducts. The cycloadditions were completely regioselective to give the hitherto unreported 3,4-dihydro-2H, 4′ H-spiro[benzo[f][1,2]thiazepine-5, 5′-isoxazole] 1,1-dioxide cycloadduct. Where the N-substituent on the sulfonamide cycloaddition precursor was a 2-substituted arene, the resulting atropisomerism along the N-aryl bond led to facial selectivity in the cycloaddition reaction, with greater than 90% diastereoselectivity. CSIRO 2014.