158330-91-7

Basic information

• Product Name: 5-BROMO-1-CHLOROINDANE
• Synonyms: 5-BROMO-1-CHLOROINDANE;5-BroMo-1-chloro-2,3-dihydro-1H-indene
• CAS NO: 158330-91-7
• Molecular Formula: C₉H₈BrCl
• Molecular Weight: 231.52
• Mol File: 158330-91-7.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-BROMO-1-CHLOROINDANE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-1-CHLOROINDANE(158330-91-7)
• EPA Substance Registry System: 5-BROMO-1-CHLOROINDANE(158330-91-7)

Safety Data

• Hazardous Substances Data: 158330-91-7(Hazardous Substances Data)

Usage

Description

5-BROMO-1-CHLOROINDANE, a halogenated indane derivative with the molecular formula C9H7BrCl, is a chemical compound that is widely recognized for its high reactivity. It is commonly utilized in the research and synthesis of pharmaceuticals and agrochemicals, serving as a crucial building block in the creation of more complex organic compounds. Its applications extend to the manufacturing of dyes and pigments, and it holds promise in the development of new drugs and materials, making it a significant player in the realm of organic chemistry. Furthermore, 5-BROMO-1-CHLOROINDANE has been the subject of studies exploring its potential biological and pharmacological activities.

Uses

Used in Pharmaceutical Research and Synthesis:
5-BROMO-1-CHLOROINDANE is used as a key intermediate in the synthesis of pharmaceuticals for its high reactivity, enabling the development of more complex organic compounds that can be utilized in medicinal chemistry.
Used in Agrochemical Research and Synthesis:
In the agrochemical industry, 5-BROMO-1-CHLOROINDANE is employed as a building block for the synthesis of various agrochemicals, contributing to the development of new pesticides and other agricultural products.
Used in Dye and Pigment Manufacturing:
5-BROMO-1-CHLOROINDANE is used as a component in the production of dyes and pigments, where its chemical properties contribute to the color and stability of these products.
Used in the Development of New Drugs:
5-BROMO-1-CHLOROINDANE is utilized in the research and development of new drugs, potentially leading to the discovery of novel therapeutic agents with improved efficacy and safety profiles.
Used in the Development of New Materials:
This chemical compound is also used in the development of new materials, where its unique properties can be harnessed to create innovative products with specific applications.
Used in Organic Chemistry Research:
5-BROMO-1-CHLOROINDANE is used as a subject of study in organic chemistry, where its potential biological and pharmacological activities are being explored for future applications in various fields.

Upstream product

• 34598-49-7 5-Bromo-1-indanone 
• 34598-50-0 5-bromo-1-indanol 

Downstream Products

• 185122-74-1 5-bromo-2,3-dihydro-1H-inden-1-one oxime 
• 1188174-30-2 5-bromo-2,3-dihydro-1H-indene-1-carbonitrile 
• 1423683-70-8 C₂₉H₂₅ClN₂O₅ 
• 1423683-72-0 C₂₉H₂₅ClN₂O₅ 
• 1423689-48-8 C₂₉H₂₅ClN₂O₅ 
• 1423689-45-5 C₃₀H₂₇ClN₂O₅ 
• 1423700-47-3 C₁₇H₂₃BO₄ 
• 1232062-02-0 1-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}-2,3-dihydro-1H-indene-5-carboxamide 
• 1232062-10-0 (1S)-1-(4-Methylpiperazin-1-yl)-N-(4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl)-2,3-dihydro-1H-indene-5-carboxamide 
• 1232061-78-7 N-(4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl)-1-piperazin-1-yl-2,3-dihydro-1H-indene-5-carboxamide 
• 1232061-74-3 tert-Butyl 4-{5-[({4-Methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}amino) carbonyl]-2,3-dihydro-1H-inden-1-yl}piperazin-1-carboxylate 
• 929713-38-2 methyl 3-(4-(5-bromo-2,3-dihydro-1H-inden-1-yloxy)phenyl)-3-(1H-pyrazol-1-yl)propanoate 
• 929713-35-9 (3S)-methyl 3-(4-(5-bromo-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoate 

Relevant articles and documents

PERIPHERAL ALKYL AND ALKENYL CHAINS EXTENDED BENZENE DERIVATIVES AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME

The compounds represented by Formula (I), which are peripheral alkyl and alkenyl chains extended benzene derivatives, are useful as dual autotaxin (ATX) / histone deacetylase (HD AC) inhibitors. These compounds may be included in a pharmaceutical composition along with a pharmaceutically acceptable carrier, and be used in a therapeutically effective amount for prophylaxis or treatment of various diseases and disorders.

LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS

Compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or diagnose diseases, disorders, or conditions associated with one or more of the lysophosphatidic acid receptors are provided.

Discovery of INCB9471, a potent, selective, and orally bioavailable CCR5 antagonist with potent anti-HIV-1 activity

To identify a CCR5 antagonist as an HIV-1 entry inhibitor, we designed a novel series of indane derivatives based on conformational considerations. Modification on the indane ring led to the discovery of compound 22a (INCB9471) that exhibited high affinit