1588-44-9Relevant articles and documents
Cobalt-catalyzed coupling reaction of alkyl halides with allylic grignard reagents
Tsuji, Takashi,Yorimitsu, Hideki,Oshima, Koichiro
, p. 4137 - 4139 (2002)
Facile construction of quaternary carbon centers: The cobalt-catalyzed coupling reaction of not only primary and secondary but also tertiary alkyl halides with allylic Grignard reagents proceeds smoothly (see scheme; dppp = 1,3-bis(diphenylphosphanyl)prop
Synthesis of alkyl sulfones from alkenes and tosylmethylphosphonium iodide through photo-promoted cc bond formation
Miura, Tomoya,Miyakawa, Sho,Moriyama, Daisuke,Murakami, Masahiro
, p. 1382 - 1385 (2020)
A new synthetic method for alkyl sulfones through CC bond formation between alkenes and tosylmethylphosphonium iodide is reported. A tosylmethyl radical is generated from the phosphonium iodide under irradiation of visible light with the aid of fac-Ir(ppy)3. It undergoes regioselective 1,2-addition across the carboncarbon double bond to afford an elongated alkyl radical, which abstracts a hydrogen atom from C6F5SH, producing an alkyl sulfone with one-carbon extension.
Visible Light/Tertiary Amine Promoted Synergistic Hydroxydifluoroacetamidation of Unactivated Alkenes under Air
Huang, Panyi,Jin, Can,Shi, Xiayue,Sun, Bin,Yan, Zhiyang,Yu, Chuanming,Zhu, Rui,Zhuang, Xiaohui
supporting information, p. 617 - 622 (2021/01/13)
An efficient and novel method for regioselective hydroxydifluoroacetamidation of alkenes with bromodifluoroacetamides has been achieved via a tandem radical pathway mediated by photoredox catalysis under metal-free conditions. This transformation proceeded smoothly in the presence of Rhodamine 6G, affording a series of α,α-difluoro-γ-hydroxyacetamides in moderate to excellent yields. The significant advantages of this protocol are the low-cost photocatalyst, readily available starting materials, synthetic convenience, and wide functional group compatibility.
Palladium and Nickel Catalyzed Suzuki Cross-Coupling with Alkyl Fluorides
Balaraman, Kaluvu,Wolf, Christian
supporting information, p. 8994 - 8999 (2021/11/20)
Suzuki cross-coupling of benzylic and unactivated aliphatic fluorides with aryl- and alkenylboronic acids has been achieved via mechanistically distinct Pd and Ni catalyzed pathways that outperform competing protodeboronation, β-hydride elimination, and h