1589553-46-7

Basic information

• Product Name: (S)-2-(1-(4-methoxyphenyl)propyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• Synonyms: (S)-2-(1-(4-methoxyphenyl)propyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 1589553-46-7
• Molecular Weight: 276.184
• Mol File: 1589553-46-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-2-(1-(4-methoxyphenyl)propyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(1-(4-methoxyphenyl)propyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1589553-46-7)
• EPA Substance Registry System: (S)-2-(1-(4-methoxyphenyl)propyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1589553-46-7)

Safety Data

• Hazardous Substances Data: 1589553-46-7(Hazardous Substances Data)

Upstream product

• 1589553-45-6 (S)-1-(4-methoxyphenyl)propyl diisopropylcarbamate 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 104-46-1 anethole 

Downstream Products

• 73854-04-3 (S)-1-(4-methoxyphenyl)propanol 

Relevant articles and documents

Chiral 2-imidazoline aniline compound as well as preparation method and application thereof

The invention provides a chiral 2-imidazoline aniline compound as well as a preparation method and application thereof. The preparation method comprises the following steps: reacting an o-nitrobenzoic acid compound as shown in a formula (1), oxalyl chloride and N, N-dimethylformamide to obtain an o-nitrobenzoyl chloride compound as shown in a formula (7); adding the hydroxyl amide derivative into a mixed solution of an amino alcohol compound as shown in a formula (2) and triethylamine to obtain a hydroxyl amide derivative as shown in a formula (3); reacting with thionyl chloride to obtain a dichloro compound as shown in a formula (4); then adding triethylamine and primary amine R2NH2 to prepare a nitroimidazoline derivative; and finally, reducing to obtain the chiral 2-imidazoline aniline compound as shown in a formula (6). The chiral 2-imidazoline aniline compound is easy to prepare, the raw materials are cheap and easy to obtain, the preparation method is simple, and the synthesized chiral ligand containing the 2-imidazoline aniline fragment can be used as a catalyst for catalyzing asymmetric hydroboration reaction of cobalt-catalyzed olefin and asymmetric hydroamination reaction of cobalt-catalyzed non-activated terminal olefin.

Stereospecific conversion of alcohols into pinacol boronic esters using lithiation-borylation methodology with pinacolborane

The synthesis of primary and secondary pinacol boronic esters via lithiation-borylation of carbamates and benzoates with pinacolborane is described. This new protocol enables the highly selective synthesis of enantioenriched and geometrically defined boronic esters that cannot otherwise be accessed by alternative methodologies. This journal is the Partner Organisations 2014.