159029-63-7

Basic information

• Product Name: 2-formyl-3-hydroxy{2.2}paracyclophane
• CAS NO: 159029-63-7
• Molecular Weight: 252.313
• Mol File: 159029-63-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-formyl-3-hydroxy{2.2}paracyclophane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-formyl-3-hydroxy{2.2}paracyclophane(159029-63-7)
• EPA Substance Registry System: 2-formyl-3-hydroxy{2.2}paracyclophane(159029-63-7)

Safety Data

• Hazardous Substances Data: 159029-63-7(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 

Downstream Products

• 1126466-67-8 C₃₅H₂₉NO 
• 5817-22-1 (2S,3R)-3-hydroxyleucine 
• 87421-23-6 (2R,3S)-2-amino-3-hydroxy-4-methylpentanoic acid 
• 109120-55-0 (2R,3S)-phenylserine 
• 6254-48-4 (2S,3R)-3-phenylserine 

Relevant articles and documents

Synthesis, resolution and absolute configuration determination of (S)- and (R)-4-formyl-5-hydroxyparacyclophane and its application in the asymmetric synthesis of α-amino acids

Racemic (R,S)-4-formyl-5-hydroxyparacyclophane (FHPC) was resolved into enantiomers via its Schiff's base with (S)- and (R)-α-phenylethylamine (α-PEAM) and its absolute configuration was determined by an X-ray diffraction structural study.Scalemic FHPC or its derivatives can be used as chiral auxiliaries for the asymmetric synthesis of β-hydroxy-α-amino acids and α-methylphenylalanine with ees ranging mostly from 45 to 98percent.