1592-62-7

Basic information

• Product Name: 2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-OL
• Synonyms: Carbazol-1-ol,1,2,3,4-tetrahydro- (7CI)
• CAS NO: 1592-62-7
• Molecular Formula: C₁₂H₁₃NO
• Molecular Weight: 187.24
• Mol File: 1592-62-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-OL(1592-62-7)
• EPA Substance Registry System: 2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-OL(1592-62-7)

Safety Data

• Hazardous Substances Data: 1592-62-7(Hazardous Substances Data)

Usage

General Description

2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-OL is a chemical compound that belongs to the class of carbozole derivatives. It is a white to off-white crystalline powder with a molecular formula of C13H13NO. 2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-OL is used in various industrial and research applications, particularly in the field of organic synthesis and pharmaceutical manufacturing. It is known for its potential biological activities and has been studied for its therapeutic properties, including its ability to act as an antioxidant and inhibit certain enzymes in the body. Additionally, 2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-OL has been investigated for its potential use in the development of new drugs and materials.

Upstream product

• 3456-99-3 1-oxo-2,3,4,9-tetrahydrocarbazole 
• 49850-32-0 ethyl 4-(1H-indol-3-yl) butanoate 
• 133-32-4 4-indol-3-yl-butyric acid 
• 1687-48-5 cyclohexane 1,2-dione monophenylhydrazone 
• 62-53-3 aniline 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 942-01-8 1,2,3,4-tetrahydrocarbazole 

Downstream Products

• 882033-76-3 1-(4-chloro-phenoxy)-2,3,4,9-tetrahydro-1H-carbazole 

Relevant articles and documents

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Catalytic Enantioselective Synthesis of Tetrahydocarbazoles and Exocyclic Pictet-Spengler-Type Reactions

A synthetic strategy for the synthesis of chiral tetrahydrocarbazoles (THCAs) has been developed. The strategy relies on two types of 6-exo-trig cyclization of 3-substituted indole substrates. Enantioselective domino Friedel-Crafts-type reactions leading to THCAs can be catalyzed by chiral phosphoric acid derivatives (with up to >99% ee), and the first examples of exocyclic Pictet-Spengler reactions to form THCAs are reported.

Synthesis and SAR of substituted tetrahydrocarbazole derivatives as new NPY-1 antagonists

The SAR of a new series of tetrahydrocarbazole derivatives is described: the appropriate decoration of this template led to the identification of a new class of NPY-1 antagonists showing good in vitro potency and a promising in vivo pharmacokinetic profil