1592-70-7

Basic information

• Product Name: 4-Vinylbenzylchloride
• Synonyms: 4-vinyl lenzyl chloride;3-O-Methylkaempferol;Isokaempferide;Kaempferol 3-methylether;Kaempferol 3-O-methylether;Kaempferol-3-methylether;Kaempferol 3-monomethyl ether;3-Methylkaempferol
• CAS NO: 1592-70-7
• Molecular Formula: C₁₆H₁₂O₆
• Molecular Weight: 300.2629
• Mol File: 1592-70-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: >300℃
• Boiling Point: 586.2 °C at 760 mmHg
• Flash Point: 224.1 °C
• Appearance: /
• Density: 1.58 g/cm³
• Storage Temp.: ?20°C
• PKA: 6.34±0.40(Predicted)
• CAS DataBase Reference: 4-Vinylbenzylchloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Vinylbenzylchloride(1592-70-7)
• EPA Substance Registry System: 4-Vinylbenzylchloride(1592-70-7)

Safety Data

• Hazard Codes: T,N
• Statements: 25-50
• Safety Statements: 45-61
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 1592-70-7(Hazardous Substances Data)

Usage

Uses

Isokaempferide is a bioactive flavonoid with antioxidant and anticholinesterase activity.

Definition

ChEBI: A trihydroxyflavone that is apigenin substituted by a methoxy group at position 3.

Upstream product

• 55317-02-7 2-methoxy-1-(2,4,6-trihydroxyphenyl)ethanone 
• 205652-96-6 4-benzoyloxy-benzoic acid-anhydride 
• 520-18-3 kaempferol 
• 16274-11-6 3,5,7-triacetoxy-2-(4-acetoxy-phenyl)-chromen-4-one 
• 911212-17-4 C₂₃H₂₂O₁₂ 
• 58860-84-7 4-(benzoyloxy)benzoyl chloride 
• 1486-49-3 p-(benzyloxy)benzoic acid anhydride 
• 1486-59-5 4'-(benzyloxy)-5,7-dihydroxy-3-methoxyflavone 

Downstream Products

• 3301-49-3 kumatakenin 
• 15486-34-7 5-hydroxy-3,4',7-trimethoxyflavone 

Relevant articles and documents

Flavonol glycosides from Centaurea furfuracea. Antiplasmodial and cytotoxic activities

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4'-Hydroxy-3-methoxyflavones with potent antipicornavirus activity

4'-Hydroxy-3-methoxyflavones are natural compounds with known antiviral activities against picornaviruses such as poliomyelitis and rhinoviruses. In order to establish a structure-activity relationship a series of analogues were synthesized, and their antiviral activities and cytotoxicities were compared with those of flavones from natural origin. The 4'-hydroxyl and 3-methoxyl groups, a substitution in the 5 position and a polysubstituted A ring appeared to be essential requirements for a high activity. The most interesting compound was 4',7-dihydroxy-3-methoxy-5,6-dimethylflavone possessing in vitro TI99 values of > 1000 and > 200 against poliovirus type 1 and rhinovirus type 15, respectively. This compound was also active against other rhinovirus serotypes (2, 9, 14, 29, 39, 41, 59, 63, 70, 85, and 89) tested, having MIC50 values ranging from 0.016 to 0.5 μg/mL. Finally in contrast to quercetin it showed to be not mutagenic in concentrations up to 2.5 mg in the Ames test.