1594769-89-7

Basic information

• Product Name: C₂₈H₃₇N₃O₆
• CAS NO: 1594769-89-7
• Molecular Weight: 511.618
• Mol File: 1594769-89-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₈H₃₇N₃O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₃₇N₃O₆(1594769-89-7)
• EPA Substance Registry System: C₂₈H₃₇N₃O₆(1594769-89-7)

Safety Data

• Hazardous Substances Data: 1594769-89-7(Hazardous Substances Data)

Upstream product

• 3338-32-7 Z-Asp(OtBu)-OSu 
• 3397-32-8 N-(benzyloxycarbonyl)-phenylalanine-N-hydroxysuccinimide ester 
• 1197840-72-4 H-Asp(OtBu)-NHPr 
• 1594769-73-9 C₁₉H₂₈N₂O₅ 

Downstream Products

• 1594769-97-7 C₂₀H₃₁N₃O₄ 
• 1594770-00-9 C₄₅H₅₉N₅O₁₀ 
• 1594769-59-1 C₃₇H₄₃N₅O₁₀ 
• 1594770-11-2 C₄₅H₅₉N₅O₁₀ 
• 1594769-70-6 ZAspPhePheAspNHPr 

Relevant articles and documents

Mechanistic insight into the lability of the benzyloxycarbonyl (Z) group in N-protected peptides under mild basic conditions

An unexpected lability of the benzyloxycarbonyl (Z) protecting group under mild basic conditions at room temperature is explained by a mechanism based on anchimeric assistance. It is found that the vicinal amide group stabilises the tetrahedral intermediate formed after nucleophilic addition of hydroxide to the carbonyl of the Z group. This effect operates in N-protected tripeptides and tetrapeptides but Z-protected dipeptides are stable under the same conditions due to blockage of the vicinal amide NH by intramolecular H-bonding with the terminal carboxylate moiety. Copyright