1601475-90-4

Basic information

• Product Name: (R)-tert-butyl 3-methyl-5-oxopiperidine-1-carboxylate
• Synonyms: (R)-tert-butyl 3-methyl-5-oxopiperidine-1-carboxylate;1-Piperidinecarboxylic acid, 3-methyl-5-oxo-, 1,1-dimethylethyl ester, (3R)-;tert-butyl 3-methyl-5-oxopiperidine-1-carboxylate
• CAS NO: 1601475-90-4
• Molecular Formula: C11H19NO3
• Molecular Weight: 213.27346
• Mol File: 1601475-90-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 298.8±33.0 °C(Predicted)
• Appearance: /
• Density: 1.060±0.06 g/cm3(Predicted)
• PKA: -1.67±0.40(Predicted)
• CAS DataBase Reference: (R)-tert-butyl 3-methyl-5-oxopiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-tert-butyl 3-methyl-5-oxopiperidine-1-carboxylate(1601475-90-4)
• EPA Substance Registry System: (R)-tert-butyl 3-methyl-5-oxopiperidine-1-carboxylate(1601475-90-4)

Safety Data

• Hazardous Substances Data: 1601475-90-4(Hazardous Substances Data)

Usage

Description

(R)-tert-butyl 3-methyl-5-oxopiperidine-1-carboxylate is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and bioactive molecules. It is characterized by its unique molecular structure, which includes a piperidine ring with a carboxylate group and a tert-butyl group, making it a versatile building block in medicinal chemistry.

Uses

Used in Pharmaceutical Industry:
(R)-tert-butyl 3-methyl-5-oxopiperidine-1-carboxylate is used as a reactant for the synthesis of novel inhibitors of HDM2-p53 protein-protein interactions. These inhibitors play a crucial role in the development of potential cancer therapeutics, as they can modulate the interaction between HDM2 and p53, which is a critical regulatory pathway in tumor suppression and cell cycle control.