1602636-73-6

Basic information

• Product Name: 2-(4-methoxyphenyl)-1,4-diphenyl-1H-imidazole
• Synonyms: 2-(4-methoxyphenyl)-1,4-diphenyl-1H-imidazole
• CAS NO: 1602636-73-6
• Molecular Weight: 326.398
• Mol File: 1602636-73-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenyl)-1,4-diphenyl-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-1,4-diphenyl-1H-imidazole(1602636-73-6)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-1,4-diphenyl-1H-imidazole(1602636-73-6)

Safety Data

• Hazardous Substances Data: 1602636-73-6(Hazardous Substances Data)

Upstream product

• 102-96-5 (2-nitroethenyl)benzene 
• 4450-64-0 N₁-phenyl-4-methoxy-1-benzenecarboximidamide 
• 874-90-8 4-methoxybenzonitrile 
• 62-53-3 aniline 
• 20718-17-6 2-(dimethyl(oxo)-λ⁶-sulfaneylidene)-1-phenylethan-1-one 
• 103-82-2 phenylacetic acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 70-11-1 α-bromoacetophenone 
• 100-42-5 styrene 

Relevant articles and documents

Acid-catalyzed synthesis of imidazole derivatives via N-phenylbenzimidamides and sulfoxonium ylides cyclization

A straightforward method to synthesize imidazole derivatives from amidines and sulfoxonium ylides catalyzed by acids is reported in this study. Specifically, catalyzed by trifluoroacetic acid in DCE solvents can improve synthesis efficiency under metal-fr

One-Pot Protocol for the Synthesis of Imidazoles and Quinoxalines using N-Bromosuccinimide

N-bromosuccinimide (NBS)-mediated one-pot, green, efficient and practical synthesis of substituted imidazoles and quinoxalines has been achieved by the reaction of styrenes with N-arylbenzamidines and o-phenylenediamines, respectively, in a water:1,4-dioxane mixture. The reaction involves formation of an α-bromo ketone as an intermediate in the presence of NBS and water, followed by condensation with the N-arylbenzamidine and o-phenylenediamine. Use of an inexpensive NBS as a bromine source as well as an oxidant, water as a solvent and readily available starting materials makes this protocol environmentally benign and economically viable. Substituted imidazoles and quinoxalines were obtained in good to excellent yields with wide functional group compatibility. (Figure presented.).

Facile synthesis of 1,2,4-trisubstituted imidazoles via aerobic copper catalyzed ligand-free [3+2] cycloaddition

A simple and facile approach to highly functionalized imidazole derivatives in moderate to good yields has been developed. This method involves copper catalyzed aerobic [3+2] cycloaddition of amidines with nitroolefins in absence of ligand. Based on observation of the intermediates, possible reaction mechanism different from the same reported approach was proposed.