1602636-82-7Relevant articles and documents
Facile synthesis of 1,2,4-trisubstituted imidazoles via aerobic copper catalyzed ligand-free [3+2] cycloaddition
Li, Wei,Tian, Weixiang Jiao Wan,Lei, Ming
, p. 386 - 392 (2014/05/20)
A simple and facile approach to highly functionalized imidazole derivatives in moderate to good yields has been developed. This method involves copper catalyzed aerobic [3+2] cycloaddition of amidines with nitroolefins in absence of ligand. Based on observation of the intermediates, possible reaction mechanism different from the same reported approach was proposed.