160278-20-6

Basic information

• Product Name: (4-THIEN-3-YLPHENYL)METHANOL
• Synonyms: [4-(3-THIENYL)PHENYL]METHANOL;(4-THIEN-3-YLPHENYL)METHANOL;AKOS BAR-1377;RARECHEM AL BD 1418;(4-Thien-3-ylphenyl)methanol 97%;3-(3-Hydroxymethylphenyl)thiophene-2-carboxylic acid;3-(4-Hydroxymethylphenyl)thiophene-2-carboxylic acid;3-(Thiophen-3-yl)benzyl alcohol
• CAS NO: 160278-20-6
• Molecular Formula: C₁₁H₁₀OS
• Molecular Weight: 190.26
• Mol File: 160278-20-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 151.5-154
• Boiling Point: 311.849°C at 760 mmHg
• Flash Point: 142.402°C
• Appearance: /
• Density: 1.204g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.622
• PKA: 14.37±0.10(Predicted)
• CAS DataBase Reference: (4-THIEN-3-YLPHENYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (4-THIEN-3-YLPHENYL)METHANOL(160278-20-6)
• EPA Substance Registry System: (4-THIEN-3-YLPHENYL)METHANOL(160278-20-6)

Safety Data

• Hazardous Substances Data: 160278-20-6(Hazardous Substances Data)

Usage

General Description

The chemical (4-Thien-3-ylphenyl)methanol, also known as thienylphenylmethanol, is a compound with a molecular formula C12H10OS. It is an organic compound that consists of a thienyl ring and a phenyl ring attached to a methanol group. It is commonly used in the synthesis of pharmaceuticals and agrochemicals as a building block in the production of various drugs and pesticides. (4-Thien-3-ylphenyl)methanol has also been studied for its potential biological activities, including its anti-cancer and anti-inflammatory properties. It is important to handle this chemical with caution and adhere to proper safety protocols when working with it.

InChI:InChI=1/C11H10OS/c12-7-9-1-3-10(4-2-9)11-5-6-13-8-11/h1-6,8,12H,7H2

Upstream product

• 873-75-6 4-bromobenzenemethanol 
• 119405-65-1 tri-n-butyl(thien-3-yl)tin 
• 160278-19-3 tert-butyldimethyl[(4-thien-3-ylbenzyl)oxy]silane 
• 29886-64-4 4-(thiophen-3-yl)benzoic acid 
• 20608-91-7 4-(thien-3-yl)benzoic acid methyl ester 
• 16939-05-2 3-(4-tolyl)thiophene 
• 87736-74-1 4-(tert-butyldimethylsiloxymethyl)bromobenzene 
• 164399-47-7 4-(3-thienyl)benzyl acetate 

Downstream Products

• 108912-09-0 3-(4-bromomethyl-phenyl)thiophene 
• 1439366-96-7 [4-(3-thienyl)-phenyl]-methyl N-[(2S,3R)-2-methyl-4-oxo-oxetan-3-yl]-carbamate 
• 1439368-16-7 (2R,3S)-3-hydroxy-2-[({[4-(thiophen-3-yl)phenyl]methoxy}carbonyl)amino]butanoic acid 
• 1439368-13-4 2-pyridyl [4-(3-thienyl)-phenyl]-methyl carbonate 
• 1439368-14-5 [4-(3-thienyl)-phenyl]-methyl 2-oxopyridine-1-carboxylate 
• 197974-45-1 1-(4-[Thien-3-yl]phenylmethyl)-5-(4-cyanobenzyl)imidazole hydrochloride salt 
• 179055-54-0 Cycloheptyl-(4-thiophen-3-yl-benzyl)-amine 
• 157730-74-0 4-(thiophene-3-yl)benzaldehyde 
• 164399-49-9 2,3-epoxy-4-(3-thienyl)-benzyloxypropane 

Relevant articles and documents

Disubstituted beta-lactones as inhibitors of N-acylethanolamine acid amidase (NAAA)

The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder.

DISUBSTITUTED BETA-LACTONES AS INHIBITORS OF N-ACYLETHANOLAMINE ACID AMIDASE (NAAA)

The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder.

Inhibitors of farnesyl-protein transferase

The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invent