160280-70-6

Basic information

• Product Name: Hexacosanamide, N-[(1S,2S,3R)-1-(hydroxymethyl)-2,3-bis(phenylmethoxy)heptadecyl]-
• CAS NO: 160280-70-6
• Molecular Formula: C58H101NO4
• Molecular Weight: 876.444
• Mol File: 160280-70-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Hexacosanamide, N-[(1S,2S,3R)-1-(hydroxymethyl)-2,3-bis(phenylmethoxy)heptadecyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexacosanamide, N-[(1S,2S,3R)-1-(hydroxymethyl)-2,3-bis(phenylmethoxy)heptadecyl]-(160280-70-6)
• EPA Substance Registry System: Hexacosanamide, N-[(1S,2S,3R)-1-(hydroxymethyl)-2,3-bis(phenylmethoxy)heptadecyl]-(160280-70-6)

Safety Data

• Hazardous Substances Data: 160280-70-6(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 201002-41-7 (2R,3S,4R)-2-azidooctadecane-1,3,4-triol 
• 201002-48-4 C₃₇H₅₁N₃O₃ 
• 201002-42-8 C₅₁H₆₃N₃O₃ 
• 160280-63-7 Methanesulfonic acid (R)-1-[(4R,5R)-2,2-dimethyl-5-((E)-tetradec-1-enyl)-[1,3]dioxolan-4-yl]-2-trityloxy-ethyl ester 
• 160280-64-8 Methanesulfonic acid (E)-(1R,2R,3R)-2,3-dihydroxy-1-hydroxymethyl-heptadec-4-enyl ester 
• 160280-68-2 (1S,2S,3R)-2,3-Bis-benzyloxy-1-trityloxymethyl-heptadecylamine 
• 160280-65-9 (2R,3R,4R)-1,3,4-trihydroxyoctadecan-2-yl methanesulfonate 
• 202812-10-0 (2S,3S,4S)-2-azido-3,4-di-O-benzyl-octadecan-1,3,4-triol 
• 160280-67-1 (2S,3S,4R)-2-azido-3,4-di-O-benzyl-1-O-trityl-1,3,4-octadecanetriol 
• 160280-66-0 (2S,3S,4R)-2-azido-1-(trityloxy)octadecane-3,4-diol 
• 117168-59-9 (2S,3S,4R)-2-azido-1,3,4-octadecanetriol 
• 100-39-0 benzyl bromide 
• 506-46-7 1-hexacosanoic acid 

Downstream Products

• 176020-22-7 (2S,3S,4R)-3,4-di-O-benzyl-N-hexacosanoyl-1-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-2-amino-1,3,4-octadecanetriol 
• 57-50-1 Sucrose 
• 1056025-04-7 C₆₆H₁₀₄N₂O₅ 
• 1089187-98-3 (2S,3S,4R)-3,4-di-O-benzyl-1-O-(6-azido-2,3,4-tri-O-benzyl-6-deoxy-α-D-galactopyranosyl)-2-hexacosylamino-octadecane-1,3,4-triol 
• 1448529-93-8 (2R,3S,4R)-2-hexacosylamino-3,4-di-O-benzyloctadecanoic acid 

Relevant articles and documents

Design and synthesis of new KRN7000 analogues

Presented by CD1d protein, KRN7000, a potent synthetic α- galactosylceramide, is known to stimulate the iNKT cells to produce different bioactive cytokines. Six new KRN7000 analogues, in which the amide bond in KRN7000 is replaced with O, NH, or ester groups incorporating variation of the acyl chain, or possessing an additional four-atom linker between the galactose and phytosphingosine moiety, were designed and synthesized. The synthetic compounds were evaluated for their ability to stimulate cytokine release and the preliminary structure-activity relationships were discussed. The synthetic strategy will benefit the construction of more KRN7000 derivatives, which may contribute to cytokine profile bias.

AMINOCYCLITOL COMPOUNDS, PROCESS FOR OBTAINING THEM AND USES

Aminocyclitol compounds and uses thereof as pharmaceutical compositions for the treatment of diseases associated with alterations in iNKT cells, more specifically autoimmune diseases, cancer, infections caused by pathogenic microorganisms or inflammatory

HEPATITIS C VIRUS INHIBITOR COMPRISING ALPHA-GLYCOSYLCERAMIDE AS THE ACTIVE INGREDIENT

This invention provides a growth inhibitor of human hepatitis C virus comprising, as an active ingredient, α-glycosylceramide used for patients infected with the aforementioned viruses. This inhibitor of hepatitis C virus comprises, as an active ingredien