160410-56-0

Basic information

• Product Name: N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-allyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-L-threonine pentafluorophenyl ester
• CAS NO: 160410-56-0
• Molecular Weight: 878.758
• Mol File: 160410-56-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-allyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-L-threonine pentafluorophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-allyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-L-threonine pentafluorophenyl ester(160410-56-0)
• EPA Substance Registry System: N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-allyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-L-threonine pentafluorophenyl ester(160410-56-0)

Safety Data

• Hazardous Substances Data: 160410-56-0(Hazardous Substances Data)

Upstream product

• 86061-06-5 N^α-(9-fluorenylmethoxycarbonyl)-L-threonine pentafluorophenyl ester 
• 160410-53-7 3,4,6-tri-O-acetyl-2-allyloxycarbonylamino-2-deoxy-α-D-glucopyranosyl trichloroacetimidate 
• 117088-31-0 O-tert-butyl-N^α-(fluoren-9-ylmethoxycarbonyl)-L-threonine pentafluorophenyl ester 

Downstream Products

• 160496-84-4 O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-N^α-(fluoren-9-ylmethoxycarbonyl)-L-threonine pentafluorophenyl ester 

Relevant articles and documents

Convenient Synthesis of O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-serine and -threonine Building Blocks for Solid-phase Glycopeptide Assembly

The suitably protected building blocks for solid-phase glycopeptide synthesis, Nα-Fmoc-Ser(Ac3-β-D-GlcNAc)-OPfp, 11, and Nα-Fmoc-Thr(Ac3-β-D-GlcNAc)-OPfp, 12, have been synthesized by stereoselective glycosidation of the 2-allyloxycarbonylamino glycosyl donor 7 with Nα-Fmoc-Ser-OPfp, 3, and Nα-Fmoc-Thr-OPfp, 4, followed by Pd0-catalysed allyl transfer from the N-allyloxycarbonyl group in the presence of acetic anhydride.