1605-53-4 Usage
Description
Diethylphenylphosphine is a colorless liquid that serves as a versatile catalyst in various chemical reactions due to its unique chemical properties.
Uses
Used in Chemical Industry:
Diethylphenylphosphine is used as a catalyst for selective cross-dimerization, enabling the efficient formation of specific chemical products by bringing together two monomer molecules.
Used in Pharmaceutical Industry:
Diethylphenylphosphine is used as a catalyst for carboxyl migration reactions, which are crucial in the synthesis of various pharmaceutical compounds and intermediates.
Used in Petrochemical Industry:
Diethylphenylphosphine is used as a catalyst for selective hydrogenation, a process that adds hydrogen to unsaturated hydrocarbons, which is essential in the production of various petrochemical products.
Used in Chiral Synthesis:
Diethylphenylphosphine is used as a catalyst for asymmetric induction by chiral diphosphines in ring contraction, playing a vital role in the synthesis of enantiomerically pure compounds, which are essential in the development of many pharmaceuticals and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 1605-53-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,0 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1605-53:
(6*1)+(5*6)+(4*0)+(3*5)+(2*5)+(1*3)=64
64 % 10 = 4
So 1605-53-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H15P/c1-3-11(4-2)10-8-6-5-7-9-10/h5-9H,3-4H2,1-2H3
1605-53-4Relevant articles and documents
Robinson,Tham
, p. P45 (1969)
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Henderson,W.A.,Buckler,S.A.
, p. 5794 - 5800 (1960)
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Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me3SiCl/DMI system
Kuroboshi, Manabu,Kita, Toshihito,Aono, Asuka,Katagiri, Toshimasa,Kikuchi, Seiya,Yamane, Syoko,Kawakubo, Hiromu,Tanaka, Hideo
, p. 918 - 920 (2015/02/05)
Direct reductions of phosphine oxides to the corresponding phosphines were performed successfully by using Mg/Me3SiCl/DMI system. The reduction proceeded under mild conditions and was applicable to a wide range of phosphine oxides; triarylphosphine oxides, alkyldiarylphosphine oxides, and dialkylarylphosphine oxides gave the corresponding phosphines in good to excellent yields.
General and selective copper-catalyzed reduction of tertiary and secondary phosphine oxides: Convenient synthesis of phosphines
Li, Yuehui,Das, Shoubhik,Zhou, Shaolin,Junge, Kathrin,Beller, Matthias
supporting information; experimental part, p. 9727 - 9732 (2012/07/14)
Novel catalytic reductions of tertiary and secondary phosphine oxides to phosphines have been developed. Using tetramethyldisiloxane (TMDS) as a mild reducing agent in the presence of copper complexes, PO bonds are selectively reduced in the presence of other reducible functional groups (FGs) such as ketones, esters, and olefins. Based on this transformation, an efficient one pot reduction/phosphination domino sequence allows for the synthesis of a variety of functionalized aromatic and aliphatic phosphines in good yields.