16066-97-0 Usage
Description
4-(2-Methyl-2-nitropropyl)phenol is an organic compound with the molecular formula C10H11NO3. It is a derivative of phenol, featuring a nitro group and a methyl group attached to the propyl chain. 4-(2-Methyl-2-nitropropyl)phenol is known for its potential applications in the pharmaceutical industry due to its unique chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
4-(2-Methyl-2-nitropropyl)phenol is used as an intermediate in the synthesis of beta adrenoceptor modulators. These modulators play a crucial role in regulating the activity of beta adrenoceptors, which are involved in various physiological processes, including heart rate, blood pressure, and metabolism.
Additionally, 4-(2-Methyl-2-nitropropyl)phenol is used as a norepinephrine-serotonin uptake inhibitor. This application is particularly relevant for the treatment of obesity, as it helps to regulate the levels of norepinephrine and serotonin in the brain, which are neurotransmitters that influence appetite and mood. By inhibiting their reuptake, this compound can potentially contribute to weight loss and improved mood regulation in patients suffering from obesity.
Check Digit Verification of cas no
The CAS Registry Mumber 16066-97-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,6 and 6 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 16066-97:
(7*1)+(6*6)+(5*0)+(4*6)+(3*6)+(2*9)+(1*7)=110
110 % 10 = 0
So 16066-97-0 is a valid CAS Registry Number.
16066-97-0Relevant articles and documents
Combination of a beta adrenoceptor modulator and a norepinephrine-serotonin uptake inhibitor for the treatment of obesity
Jesudason, Cynthia D.,Baker, James E.,Bryant, Robert D.,Fisher, Jack W.,O'Farrell, Libbey S.,Gaich, Gregory A.,He, Minxia M.,Kahl, Steven D.,Kriauciunas, Aidas V.,Heiman, Mark L.,Peters, Mary A.,Rito, Christopher J.,Satterwhite, Julie H.,Tinsley, Frank C.,Trankle, William G.,Shuker, Anthony J.
, p. 583 - 586 (2011)
We report the novel combination of a selective beta adrenoceptor modulator and a norepinephrine-serotonin uptake inhibitor (sibutramine) with potential for the treatment of obesity. The synthesis and characterization of 6-[4-[2-[[(2S)-3-(9H-carbazol-4-ylo
BENZOTHIAZOLONE COMPOUND
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Paragraph 38; 39, (2013/03/26)
The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form(I) a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination o
(ALPHA-SUBSTITUTED ARALKYLAMINO AND HETEROARYLALKYLAMINO) PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES
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Page/Page column 76, (2012/10/08)
Provided herein are (alpha-substituted aralkylamino or heteroarylalkylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, e.g., a compound of Formula 1, and their pharmaceutical compositions, preparation, and use as agents or drugs for treating proliferative diseases