16078-25-4 Usage
Description
(R)-(-)-3-METHYLPIPERIDINE is a chiral organic compound belonging to the class of piperidines, characterized by a six-membered nitrogen-containing ring. As a chiral molecule, it possesses a non-superimposable mirror image, with the (R)-(-)-enantiomer being the specific optical isomer in focus. (R)-(-)-3-METHYLPIPERIDINE serves as a crucial building block in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds, while also being utilized in the production of bactericides and fungicides.
Uses
Used in Pharmaceutical Industry:
(R)-(-)-3-METHYLPIPERIDINE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to form biologically active molecules, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
(R)-(-)-3-METHYLPIPERIDINE is used as a precursor in the production of agrochemicals, specifically in the creation of bactericides and fungicides, to help protect crops from various diseases and pests, ensuring increased agricultural productivity.
Used in Organic Synthesis:
(R)-(-)-3-METHYLPIPERIDINE is used as a building block in organic synthesis for its capacity to form a variety of complex organic compounds, facilitating the development of new chemical entities with diverse applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 16078-25-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,7 and 8 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 16078-25:
(7*1)+(6*6)+(5*0)+(4*7)+(3*8)+(2*2)+(1*5)=104
104 % 10 = 4
So 16078-25-4 is a valid CAS Registry Number.
16078-25-4Relevant articles and documents
Efficient asymmetric hydrogenation of pyridines
Glorius, Frank,Spielkamp, Nick,Holle, Sigrid,Goddard, Richard,Lehmann, Christian W.
, p. 2850 - 2852 (2004)
Up to four stereocenters can be created efficiently in a single step by the asymmetric hydrogenation of oxazolidinone-substituted pyridines (see scheme). Furthermore, selective chirality transfer and nondestructive cleavage of the chiral auxiliary occur under the same reaction conditions, making an additional cleavage step unnecessary.
Synthesis of: N -heterocycles from diamines via H2-driven NADPH recycling in the presence of O2
Al-Shameri, Ammar,Borlinghaus, Niels,Weinmann, Leonie,Scheller, Philipp N.,Nestl, Bettina M.,Lauterbach, Lars
, p. 1396 - 1400 (2019/03/26)
Herein, we report an enzymatic cascade involving an oxidase, an imine reductase and a hydrogenase for the H2-driven synthesis of N-heterocycles. Variants of putrescine oxidase from Rhodococcus erythropolis with improved activity were identified. Substituted pyrrolidines and piperidines were obtained with up to 97% product formation in a one-pot reaction directly from the corresponding diamine substrates. The formation of up to 93% ee gave insights into the specificity and selectivity of the putrescine oxidase.