1609577-13-0

Basic information

• Product Name: 4-[3-methoxy-4-(3-methylpyrazin-2-yl)phenoxy]furo[3,2-c]pyridine
• Synonyms: 4-[3-methoxy-4-(3-methylpyrazin-2-yl)phenoxy]furo[3,2-c]pyridine
• CAS NO: 1609577-13-0
• Molecular Weight: 333.346
• Mol File: 1609577-13-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[3-methoxy-4-(3-methylpyrazin-2-yl)phenoxy]furo[3,2-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[3-methoxy-4-(3-methylpyrazin-2-yl)phenoxy]furo[3,2-c]pyridine(1609577-13-0)
• EPA Substance Registry System: 4-[3-methoxy-4-(3-methylpyrazin-2-yl)phenoxy]furo[3,2-c]pyridine(1609577-13-0)

Safety Data

• Hazardous Substances Data: 1609577-13-0(Hazardous Substances Data)

Upstream product

• 120984-76-1 2-bromo-3-methyl-pyrazine 
• 1609581-05-6 4-[3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]furo[3,2-c]pyridine 

Downstream Products

• 1609578-47-3 4-{3-[(3-cyclopropyl-1,2,4-oxadiazol-5-yl)methoxy]-4-(3-methylpyrazin-2-yl)phenoxy}furo[3,2-c]pyridine 
• 1609581-41-0 5-(furo[3,2-c]pyridin-4-yloxy)-2-(3-methylpyrazin-2-yl)phenol 

Relevant articles and documents

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof and N-oxides thereof; processes and intermediates for preparation of; and compositions and uses thereof. The present invention further provides D1 agonists with reduced D1R desensitization, D1 agonists with a reduced β- arrestin recruitment activity relative to Dopamine, D1 agonists interacting significantly with the Ser188 but not significantly with the Ser202 of a D1R when binding to the D1R, D1 agonists interacting less strongly with the Asp103 and interacting less strongly with the Ser198 of a D1R when binding to the D1R, and their uses.