160978-20-1

Basic information

• Product Name: (2R,4S)-4-Benzyl-2-tert-butyl-4-(2-hydroxy-ethyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester
• Synonyms: (2R,4S)-4-Benzyl-2-tert-butyl-4-(2-hydroxy-ethyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester
• CAS NO: 160978-20-1
• Molecular Weight: 361.438
• Mol File: 160978-20-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R,4S)-4-Benzyl-2-tert-butyl-4-(2-hydroxy-ethyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4S)-4-Benzyl-2-tert-butyl-4-(2-hydroxy-ethyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester(160978-20-1)
• EPA Substance Registry System: (2R,4S)-4-Benzyl-2-tert-butyl-4-(2-hydroxy-ethyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester(160978-20-1)

Safety Data

• Hazardous Substances Data: 160978-20-1(Hazardous Substances Data)

Upstream product

• 75-21-8 oxirane 
• 147240-29-7 (2R,4R)-4-Benzyl-2-tert-butyl-5-oxo-oxazolidine-3-carboxylic acid allyl ester 

Downstream Products

• 173092-07-4 (S)-2-Allyloxycarbonylamino-2-benzyl-4-(2-methoxy-ethoxymethoxy)-butyric acid methyl ester 
• 173092-06-3 (2R,4S)-4-Benzyl-2-tert-butyl-4-[2-(2-methoxy-ethoxymethoxy)-ethyl]-5-oxo-oxazolidine-3-carboxylic acid allyl ester 

Relevant articles and documents

Pyrrolinone-based HIV protease inhibitors. Design, synthesis, and antiviral activity: Evidence for improved transport

Pyrrolinone-based peptidomimetics, the first mimics of β-strands, are potent inhibitors of HIV-1 protease. Importantly, the bis(pyrrolinones) described herein proved to be more active in cellular antiviral assays compared with an analogous peptide-derived