160978-35-8

Basic information

• Product Name: [1-benzylcarbamoyl-2-(2-benzylcarbamoyl-2-tert-butoxycarbonylamino-ethyldisulfanyl)-ethyl]-carbamic acid tert-butyl ester
• Synonyms: [1-benzylcarbamoyl-2-(2-benzylcarbamoyl-2-tert-butoxycarbonylamino-ethyldisulfanyl)-ethyl]-carbamic acid tert-butyl ester
• CAS NO: 160978-35-8
• Molecular Weight: 618.819
• Mol File: 160978-35-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [1-benzylcarbamoyl-2-(2-benzylcarbamoyl-2-tert-butoxycarbonylamino-ethyldisulfanyl)-ethyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [1-benzylcarbamoyl-2-(2-benzylcarbamoyl-2-tert-butoxycarbonylamino-ethyldisulfanyl)-ethyl]-carbamic acid tert-butyl ester(160978-35-8)
• EPA Substance Registry System: [1-benzylcarbamoyl-2-(2-benzylcarbamoyl-2-tert-butoxycarbonylamino-ethyldisulfanyl)-ethyl]-carbamic acid tert-butyl ester(160978-35-8)

Safety Data

• Hazardous Substances Data: 160978-35-8(Hazardous Substances Data)

Upstream product

• 160978-33-6 N^α-tert-butoxycarbonyl-S-allyloxycarbonylaminomethyl-L-cysteine benzylamide 
• 10389-65-8 di-t-butoxycarbonyl-L-cystine 
• 100-46-9 benzylamine 

Relevant articles and documents

Allylic protection of thiols and cysteine: I: The allyloxycarbonylaminomethyl group

S-allyloxycarbonylaminomethyl derivatives of thiols in general and cysteine in particular are readily deprotected by palladium catalysed hydrostannolysis with tributyltin hydride in the presence of acetic acid. They are perfectly stable in the basic conditions (piperidine/DMF) of Fmoc group removal but tend to decompose, albeit slowly, in the acidic conditions (TFA/CH2Cl2) of t-Bu and Boc groups removal.