160983-67-5

Basic information

• Product Name: tert-butyl 4-(2-nitrophenyl)-3-oxobutanoate
• Synonyms: tert-butyl 4-(2-nitrophenyl)-3-oxobutanoate
• CAS NO: 160983-67-5
• Molecular Weight: 279.293
• Mol File: 160983-67-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(2-nitrophenyl)-3-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(2-nitrophenyl)-3-oxobutanoate(160983-67-5)
• EPA Substance Registry System: tert-butyl 4-(2-nitrophenyl)-3-oxobutanoate(160983-67-5)

Safety Data

• Hazardous Substances Data: 160983-67-5(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 22751-23-1 (2-nitrophenyl)acetyl chloride 
• 75-65-0 tert-butyl alcohol 
• 99185-25-8 4-(2-nitro-phenyl)-acetoacetic acid 
• 3740-52-1 2-(2-nitrophenyl)acetic acid 

Downstream Products

• 1431726-78-1 (1R,5S,8R)-tert-butyl 7-hydroxy-2-(4-methylphenylsulfonyl)-8-(2-nitrophenyl)-2-azabicyclo[3.3.1]non-6-ene-6-carboxylate 

Relevant articles and documents

Transition-metal-free [3 + 3] annulation of indol-2-ylmethyl carbanions to nitroarenes. A novel synthesis of indolo[3,2-b]quinolines (quindolines)

Indol-2-ylmethyl carbanions stabilized by alkoxycarbonyl, cyano or benzenesulfonyl groups react with nitroarenes to form σH-adducts, which in the presence of base (triethylamine or DBU) and trimethylchlorosilane transform into indolo[3,2-b]quinoline derivatives in moderate to good yields.

Intramolecular Diels-Alder Reactions of Pyranoindol-3-ones. Preparation of -Annelated Carbazoles

The pyranoindol-3-ones (5), readily prepared from t-butyl indole-2-acetate (2) in three steps, undergo facile intramolecular Diels-Alder reaction on heating to give, after loss of carbon dioxide, the -annelated carbazoles (6).