1610846-52-0

Basic information

• Product Name: 3,3,3-trifluoro-1-(4-methoxyphenyl)-2-methylpropan-1-one
• Synonyms: 3,3,3-trifluoro-1-(4-methoxyphenyl)-2-methylpropan-1-one
• CAS NO: 1610846-52-0
• Molecular Weight: 232.202
• Mol File: 1610846-52-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3,3,3-trifluoro-1-(4-methoxyphenyl)-2-methylpropan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3,3-trifluoro-1-(4-methoxyphenyl)-2-methylpropan-1-one(1610846-52-0)
• EPA Substance Registry System: 3,3,3-trifluoro-1-(4-methoxyphenyl)-2-methylpropan-1-one(1610846-52-0)

Safety Data

• Hazardous Substances Data: 1610846-52-0(Hazardous Substances Data)

Upstream product

• 696-62-8 para-iodoanisole 
• 887144-94-7 Togni's reagent II 
• 1610846-39-3 triethyl((1-(4-methoxyphenyl)prop-1-en-1-yl)oxy)silane 
• 75-63-8 Bromotrifluoromethane 
• 104-46-1 anethole 
• 2749-94-2 1-methoxy-4-(prop-1-yn-1-yl)benzene 
• 2926-29-6 Langlois reagent 
• 4180-23-8 E-1-(4'-methoxyphenyl)prop-1-ene 

Relevant articles and documents

Method for preparing hydroxyl and trifluoromethyl substituted compounds through reaction of olefin and trifluo-romethyl bromide

The invention discloses a method for preparing hydroxyl and trifluoromethyl substituted compounds through olefin addition reaction. According to the method, a compound containing carbon-carbon doublebonds and trifluo-romethyl bromide are taken as raw materials, a metal salt-tertiary amine system is taken as a catalyst, air is taken as an oxidizing agent, carbon-carbon double bonds can be subjected to addition reaction, and compounds with hydroxyl substitution and trifluoromethyl substitution at the same time are prepared; wherein the metal salt is one or more selected from a cobalt salt, a silver salt, a bismuth salt, a nickel salt, an iron salt or a copper salt; the tertiary amine is N-isopropyl-N-methyl-tert-butylamine or N, N-diisopropylethylamine. According to the method, the metal salt-tertiary amine system is taken as a catalyst for the first time, hydroxyl substitution and trifluoromethyl substitution of olefins are realized, one-step reaction is enough, reaction process conditions are mild, reaction raw materials are cheap and easily available, cost is low, reaction substrates have strong applicability, and can participate in the reaction as long as carbon-carbon double bonds exist in the structures, and are not influenced by substituent groups on double bond carbon atoms, and the product yield is high.

Strongly Reducing (Diarylamino)anthracene Catalyst for Metal-Free Visible-Light Photocatalytic Fluoroalkylation

Well-defined 9,10-bis(di(p-tert-butylphenyl)amino)anthracene serves as a photocatalyst for radical fluoroalkylation under visible light irradiation. The diarylamine (Donor)-anthracene (π conjugated system)-diarylamine (Donor) scaffolds are easily accessed

Sunlight-driven trifluoromethylation of olefinic substrates by photoredox catalysis: A green organic process

The principles and utility of photoredox catalysis in organic synthesis are described. After a brief description of the features of the two types of catalytic photoredox processes following the reductive quenching cycle (RQC) and the oxidative quenching cycle (OQC), the discussion is focused on organic transformations based on OQC, in particular the trifluoromethylation of olefinic substrates with electrophilic trifluoromethylating reagents furnishing solvolytic addition products and substitution products. It is concluded that catalytic photoredox systems are green from the point of view of harmfulness, safety, and energy source (visible light, including sunlight). Future prospects of photoredox catalysis will be also discussed.