1612888-17-1Relevant articles and documents
Metal-free (Boc)2O-mediated C4-selective direct indolation of pyridines using TEMPO
Qin, Wen-Bing,Zhu, Jia-Yi,Kong, Yu-Bo,Bao, Yun-Hong,Chen, Zheng-Wang,Liu, Liang-Xian
supporting information, p. 4252 - 4259 (2014/06/10)
Direct metal-free C-4-selective indolation of pyridines is achieved for the first time using TEMPO and (Boc)2O. A variety of substituents on both indoles and pyridines are tolerated to give 3-(pyridin-4-yl)-1H-indole derivatives in moderate to excellent yields. This finding provides a novel approach for developing metal-free C-H functionalization of pyridines. This journal is the Partner Organisations 2014.