1613-97-4

Basic information

• Product Name: (E)-1-(4-bromophenyl)-N-phenylmethanimine
• Synonyms: (E)-1-(4-bromophenyl)-N-phenylmethanimine
• CAS NO: 1613-97-4
• Molecular Weight: 260.133
• Mol File: 1613-97-4.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: (E)-1-(4-bromophenyl)-N-phenylmethanimine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(4-bromophenyl)-N-phenylmethanimine(1613-97-4)
• EPA Substance Registry System: (E)-1-(4-bromophenyl)-N-phenylmethanimine(1613-97-4)

Safety Data

• Hazardous Substances Data: 1613-97-4(Hazardous Substances Data)

Usage

Description

(E)-1-(4-bromophenyl)-N-phenylmethanimine, with the molecular formula C13H10BrN, is a chemical compound belonging to the class of imines. It features a carbon-nitrogen double bond and is characterized by the presence of a 4-bromophenyl group and a phenyl group attached to the nitrogen atom. (E)-1-(4-bromophenyl)-N-phenylmethanimine is known for its unique chemical structure and reactivity, which makes it a valuable building block in organic synthesis and pharmaceutical research.

Uses

Used in Organic Synthesis:
(E)-1-(4-bromophenyl)-N-phenylmethanimine is used as a key building block in the synthesis of various organic compounds. Its unique structure and reactivity allow for the creation of a wide range of molecules with different properties and applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (E)-1-(4-bromophenyl)-N-phenylmethanimine serves as an important intermediate for the development of new drugs. Its chemical properties make it a promising candidate for the design and synthesis of novel therapeutic agents.
Used in Material Development:
Due to its potential applications in creating new materials with unique properties, (E)-1-(4-bromophenyl)-N-phenylmethanimine is also utilized in the field of material science. Researchers can leverage its chemical structure to develop innovative materials for various industrial applications.
Used in Biological Studies:
(E)-1-(4-bromophenyl)-N-phenylmethanimine may possess biological properties that can be explored in the study of organic reactions and mechanisms. Its potential use in biological research could lead to a better understanding of its interactions with biological systems and the development of new bioactive compounds.
Used in the Study of Organic Reactions and Mechanisms:
The unique chemical structure of (E)-1-(4-bromophenyl)-N-phenylmethanimine makes it an interesting subject for research in organic chemistry. It can be used to investigate various reaction pathways and mechanisms, contributing to the advancement of knowledge in the field.

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 62-53-3 aniline 
• 873-75-6 4-bromobenzenemethanol 

Downstream Products

• 852204-40-1 (3R,4S)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-4-(3'-hydroxybiphenyl-4-yl)-1-phenylazetidin-2-one 
• 119948-35-5 3-(4-bromophenyl)-1-phenyl-3-(N-phenylamino)propan-1-one 

Relevant articles and documents

Inverse Hydroboration of Imines with NHC-Boranes Is Promoted by Diphenyl Disulfide and Visible Light

We describe a simple and efficient procedure for nucleophilic borylation of imines in the absence of a photoredox catalyst. Visible light irradiation of an acetonitrile solution of an imine, an NHC-borane, and diphenyl disulfide (10 mol %) provides various stable α-amino NHC-boranes in good yields. The reaction proceeds via addition of a nucleophilic boryl radical to an imine, followed by hydrogen abstraction from thiophenol, which is generated from NHC-borane and diphenyl disulfide.

Nickel versus Palladium in Cross-Coupling Catalysis: On the Role of Substrate Coordination to Zerovalent Metal Complexes

A detailed comparison of the effect of coordinating functional groups on the performance of Suzuki-Miyaura reactions catalysed by nickel and palladium is reported, using competition experiments, robustness screening, and density functional theory calculations. Nickel can interact with a variety of functional groups, which manifests as selectivity in competitive cross-coupling reactions. The presence of these functional groups on exogenous additives has effects on cross-coupling reactions that range from a slight improvement in yield to the complete cessation of the reaction. In contrast, palladium does not interact sufficiently strongly with these functional groups to induce selectivity in cross-coupling reactions; the selectivity of palladium-catalysed cross-coupling reactions is predominantly governed by aryl halide electronic properties.

Synergistic Photoredox Catalysis and Organocatalysis for Inverse Hydroboration of Imines

The first catalytic inverse hydroboration of imines with N-heterocyclic carbene (NHC) boranes has been realized by means of cooperative organocatalysis and photocatalysis. This catalytic combination provides a promising platform for promoting NHC-boryl radical chemistry under sustainable and radical-initiator-free conditions. The highly important functional-group compatibility and possible application in late-stage hydroborations represent an important step forward to an enhanced α-amino organoboron library.