1613393-51-3 Usage
Description
(3aR,5S)-3a,4,5,7-tetrahydro-5-Methyl-3H-pyrano[3,4-c]isoxazole is a heterocyclic compound characterized by a unique 7-membered ring system that fuses an isoxazole and a pyran ring. It is a pyranoisoxazole derivative, originating from the natural antibiotic andrastin A, which contains isoxazole. (3aR,5S)-3a,4,5,7-tetrahydro-5-Methyl-3H-pyrano[3,4-c]isoxazole has demonstrated significant pharmacological potential, particularly in its antimicrobial properties, and is a subject of interest for chemical synthesis and medicinal chemistry due to its distinctive structure and promising activity.
Uses
Used in Pharmaceutical Industry:
(3aR,5S)-3a,4,5,7-tetrahydro-5-Methyl-3H-pyrano[3,4-c]isoxazole is utilized as an antimicrobial agent for its demonstrated effectiveness against various microorganisms. Its unique structure contributes to its potential as a new class of antibiotics, which is crucial in the ongoing battle against antibiotic resistance.
Used in Chemical Synthesis:
In the field of chemical synthesis, (3aR,5S)-3a,4,5,7-tetrahydro-5-Methyl-3H-pyrano[3,4-c]isoxazole serves as a key intermediate or building block for the creation of more complex molecules with potential applications in medicine and other industries. Its unique fused ring system allows for the development of novel compounds with enhanced properties.
Used in Medicinal Chemistry Research:
(3aR,5S)-3a,4,5,7-tetrahydro-5-Methyl-3H-pyrano[3,4-c]isoxazole is employed in medicinal chemistry research to explore its pharmacological properties and to understand its mechanism of action. This research is vital for optimizing the compound's therapeutic potential and for developing new drugs based on its structure.
Check Digit Verification of cas no
The CAS Registry Mumber 1613393-51-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,1,3,3,9 and 3 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1613393-51:
(9*1)+(8*6)+(7*1)+(6*3)+(5*3)+(4*9)+(3*3)+(2*5)+(1*1)=153
153 % 10 = 3
So 1613393-51-3 is a valid CAS Registry Number.
1613393-51-3Relevant articles and documents
[1,3]thiazin-2-amine compounds as well as applications and pharmaceutical compositions thereof
-
Paragraph 0140; 0148, (2018/04/21)
The invention relates to [1,3]thiazin-2-amine compounds as well as applications and pharmaceutical compositions thereof, and belongs to the field of BACE (beta-site amyloid precursor protein cleavingenzyme) inhibitors. The [1,3]thiazid-2-amine compounds are compounds, pharmaceutically acceptable salts, stereoisomers, solvates, or prodrugs represented by a formula (I), and the formula (I) is shownin the description. The [1,3]thiazin-2-amine compounds provided by the invention have good inhibiting effects on BACE, and can be used for the preparation of medicines for treating neurodegenerativediseases such as alzheimer diseases.
TETRAHYDROPYRANO[3,4-D][1,3]OXAZIN DERIVATIVES AND THEIR USE AS BACE INHIBITORS
-
Page/Page column 43; 44; 45, (2017/04/11)
The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula (I), wherein the variables R1, R2, R3, R4 and X are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
2-AMINO-6-METHYL-4,4a,5,6-TETRAHYDROPYRANO[3,4-d][1,3]THIAZIN-8a(8H)-YL-1,3-THIAZOL-4-YL AMIDES
-
, (2015/11/17)
The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula (I), and the variable R1 is as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
