161448-76-6Relevant articles and documents
Combination of non-natural D-amino acid derivatives and allophenylnorstatine-dimethylthioproline scaffold in HIV protease inhibitors have high efficacy in mutant HIV
Nakatani, Shingo,Hidaka, Koushi,Ami, Ei'Ichi,Nakahara, Koichiro,Sato, Akihiko,Nguyen, Jeffrey-Tri,Hamada, Yoshio,Hori, Yasuko,Ohnishi, Nobuyuki,Nagai, Akinori,Kimura, Tooru,Hayashi, Yoshio,Kiso, Yoshiaki
experimental part, p. 2992 - 3004 (2009/04/05)
Several non-natural D-amino acid derivatives were introduced as P2/P3 residues in allophenylnorstatine-containing (Apns; (2S,3S)-3-amino-2-hydroxy-4- phenylbutyric acid) HIV protease inhibitors. The synthetic analogues exhibited potent inhibitory activity
