1620220-66-7

Basic information

• Product Name: C₆H₆BrFN₂O₂S
• Synonyms: C₆H₆BrFN₂O₂S
• CAS NO: 1620220-66-7
• Molecular Weight: 269.094
• Mol File: 1620220-66-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₆H₆BrFN₂O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₆H₆BrFN₂O₂S(1620220-66-7)
• EPA Substance Registry System: C₆H₆BrFN₂O₂S(1620220-66-7)

Safety Data

• Hazardous Substances Data: 1620220-66-7(Hazardous Substances Data)

Upstream product

• 351003-51-5 4-bromo-3-fluorobenzene-1-sulfonyl chloride 

Downstream Products

• 779329-61-2 1-bromo-4-(ethylsulfonyl)-2-fluorobenzene 
• 1614246-46-6 1-bromo-2-fluoro-4-(isopropylsulfonyl)benzene 
• 1614246-66-0 2-(6-chloro-4'-(ethylsulfonyl)-2'-methoxy-[1,1'-biphenyl]-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1614246-68-2 2-(4'-(ethylsulfonyl)-2',6-dimethoxy-[1,1'-biphenyl]-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1614246-14-8 5-(7-ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)-4'-(ethylsulfonyl)-2'-methoxy-[1,1'-biphenyl]-2-carbonitrile 
• 1614246-88-6 4'-(ethylsulfonyl)-2'-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)[1,1'-biphenyl]-2-ol 
• 1614246-15-9 5-(7-ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)-4'-(ethylsulfonyl)-2'-methoxy-[1,1'-biphenyl]-2-ol 
• 1614246-34-2 1-bromo-4-(ethylsulfonyl)-2-methoxybenzene 
• 1614246-36-4 2-(4-(ethylsulfonyl)-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1614245-70-3 4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxybiphenyl-3-yl)-7-ethyl-7H-imidazo[4,5-c]pyridazine 
• 1614246-47-7 1-bromo-4-(isopropylsulfonyl)-2-methoxybenzene 
• 1614246-48-8 2-(4-(isopropylsulfonyl)-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1614246-50-2 2-(6-fluoro-4'-(isopropylsulfonyl)-2'-methoxy-[1,1-biphenyl]-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1614246-56-8 2-[4-(ethylsulfonyl)-2-fluorophenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant articles and documents

Electrochemical fluorosulfonylation of styrenes

An environmentally friendly and efficient electrochemical fluorosulfonylation of styrenes has been developed. With the use of sulfonylhydrazides and triethylamine trihydrofluoride, a diverse array of β-fluorosulfones could be readily obtained. This reaction features mild conditions and a broad substrate scope, which could also be conveniently extended to a gram-scale preparation.

Chemical Compounds

The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.